In-solution behavior and protective potential of asparagine synthetase A from Trypanosoma cruzi.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2019.03.002
Abstract: l-Asparagine synthetase (AS) acts in asparagine formation and can be classified into two families: AS-A or AS-B. AS-A is mainly found in prokaryotes and can synthetize asparagine from ammonia. Distinct from other eukaryotes, Trypanosoma cruzi… read more here.
Keywords: solution behavior; trypanosoma cruzi; asparagine synthetase;
Effects of A6E Mutation on Protein Expression and Supramolecular Assembly of Yeast Asparagine Synthetase
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DOI: 10.3390/biology10040294
Abstract: Simple Summary Certain mutations causing extremely low abundance of asparagine synthetase (the enzyme responsible for producing asparagine, one of the amino acids required for normal growth and development) have been identified in humans with neurological… read more here.
Keywords: a6e mutation; synthetase; yeast asparagine; asparagine synthetase ... See more keywords
Analysis of Enzyme Activity and Cellular Function for the N80S and S480F Asparagine Synthetase Variants Expressed in a Child with Asparagine Synthetase Deficiency
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010559
Abstract: Asparagine Synthetase Deficiency (ASNSD) is a disease caused by mutations in asparagine synthetase (ASNS). Newborns exhibit microcephaly, intractable epileptic-like seizures, progressive brain atrophy, and axial hypotonia. ASNSD results in global developmental delays and premature death.… read more here.
Keywords: synthetase deficiency; asparagine synthetase; synthetase; enzyme activity ... See more keywords