The role of N-methyl-D-aspartate receptors and metabotropic glutamate receptor 5 in the prepulse inhibition paradigms for studying schizophrenia: pharmacology, neurodevelopment, and genetics.
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural pharmacology"
DOI: 10.1097/fbp.0000000000000352
Abstract: Treatments for the positive and negative symptoms of schizophrenia have been explored for decades, but no completely successful therapy has been found as yet. Metabotropic glutamate receptor 5 (mGluR5), which potentiates N-methyl-D-aspartate receptors in brain… read more here.
Keywords: methyl aspartate; genetics; metabotropic glutamate; aspartate receptors ... See more keywords
Protein quality control of N-methyl-D-aspartate receptors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.907560
Abstract: N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form via the heterotetrameric assembly of… read more here.
Keywords: protein quality; quality; quality control; methyl aspartate ... See more keywords
Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2021.797253
Abstract: Epilepsy is one of the most common neurological disorders characterized by recurrent seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N-methyl-D-aspartate receptors (NMDARs) play an important role in abnormal discharges, nerve… read more here.
Keywords: aspartate receptors; methyl aspartate; receptors nmdars; nmdars epilepsy ... See more keywords
N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00577
Abstract: The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells. Data previously published by others and us… read more here.
Keywords: receptors hematopoietic; methyl aspartate; nmdar; aspartate receptors ... See more keywords
The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081471
Abstract: (1) Background: The N-methyl-D-aspartate receptors (NMDARs) mediate fast excitatory currents leading to depolarization. Postsynaptic NMDARs are ionotropic glutamate receptors that mediate excitatory glutamate or glycine signaling in the CNS and play a primary role in… read more here.
Keywords: effect; methyl aspartate; aspartate receptors; ergotamine ... See more keywords