Functional Characterization of Secreted Aspartyl Proteases in Candida parapsilosis
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DOI: 10.1128/msphere.00484-19
Abstract: Aspartyl proteases are present in various organisms and, among virulent species, are considered major virulence factors. Host tissue and cell damage, hijacking of immune responses, and hiding from innate immune cells are the most common… read more here.
Keywords: sapp1 sapp2; aspartyl proteases; cell damage; parapsilosis ... See more keywords
Signaling Functions of Intramembrane Aspartyl-Proteases
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DOI: 10.3389/fcvm.2020.591787
Abstract: Intramembrane proteolysis is more than a mechanism to “clean” the membranes from proteins no longer needed. By non-reversibly modifying transmembrane proteins, intramembrane cleaving proteases hold key roles in multiple signaling pathways and often distinguish physiological… read more here.
Keywords: signaling functions; aspartyl proteases; intramembrane cleaving; spp sppl ... See more keywords