Physicochemical quality assessment of four asparaginases
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DOI: 10.1371/journal.pone.0326106
Abstract: L-Asparaginases (ASNases) are used for the treatment of acute lymphoblastic leukaemia. There are reports of quality problems for some therapeutic asparaginase products, especially those manufactured in middle-income countries. These products may exhibit decreased potency and/or… read more here.
Keywords: quality; physicochemical quality; asnase preparations; aspase ... See more keywords