Mac‐1 triggers neutrophil DNA extracellular trap formation to Aspergillus fumigatus independently of PAD4 histone citrullination
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a0119-009rr
Abstract: Aspergillus fumigatus (A. fumigatus) is an environmental fungus and a human pathogen. Neutrophils are critical effector cells during the fungal infections, and neutropenia is a risk factor for the development of pulmonary aspergillosis. Neutrophil extracellular… read more here.
Keywords: response fumigatus; fumigatus; aspergillus fumigatus; net release ... See more keywords
Beyond the Charge: Interplay of Nanogels' Functional Group and Zeta-Potential for Antifungal Drug Delivery to Human Pathogenic Fungus Aspergillus fumigatus.
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202400082
Abstract: The ubiquitous mold Aspergillus fumigatus (A. fumigatus) is one of the main fungal pathogens causing invasive infections in immunocompromised humans. Conventional antifungal agents exhibit limited efficacy and often cause severe side effects. Nanoparticle-based antifungal delivery… read more here.
Keywords: functional group; delivery; fumigatus; aspergillus fumigatus ... See more keywords
Aspergillus fumigatus population dynamics and sensitivity to demethylation inhibitor fungicides in whole-crop corn, high moisture corn and wet grain corn silages.
Sign Up to like & getrecommendations! Published in 2019 at "Pest management science"
DOI: 10.1002/ps.5566
Abstract: BACKGROUND Aspergillus fumigatus, the causal agent of aspergillosis in humans, is commonly present as saprophyte in various organic substrates, such as spoiled silages. Aspergillosis is generally combated with demethylation inhibitor (DMI) fungicides, but the recent… read more here.
Keywords: aspergillus fumigatus; whole crop; corn; sensitivity ... See more keywords
Triazole resistance in Aspergillus fumigatus exposed to new chiral fungicide mefentrifluconazole.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7224
Abstract: BACKGROUND Triazole resistance in human fungal pathogen Aspergillus fumigatus has been a growing challenge in clinic treatment with triazole drugs such as itraconazole. The fast evolvement of triazole-resistance in Aspergillus fumigatus in the ecosystem has… read more here.
Keywords: resistance fumigatus; aspergillus fumigatus; resistance; triazole resistance ... See more keywords
Aspergillus fumigatus DHN-Melanin.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2020_205
Abstract: Dihydroxynaphthalene melanin (DHN-melanin) is an integral component of the conidial cell wall surface, which has a central role in the pathogenicity of the major human airborne fungal pathogen Aspergillus fumigatus. Although the biosynthetic pathway for… read more here.
Keywords: aspergillus fumigatus; fumigatus dhn; dhn melanin; melanin ... See more keywords
Cytoskeletal Alteration Is an Early Cellular Response in Pulmonary Epithelium Infected with Aspergillus fumigatus Rather than Scedosporium apiospermum.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial ecology"
DOI: 10.1007/s00248-021-01750-7
Abstract: Invasive aspergillosis and scedosporiosis are life-threatening fungal infections with similar clinical manifestations in immunocompromised patients. Contrarily, Scedosporium apiospermum is susceptible to some azole derivative but often resistant to amphotericin B. Histopathological examination alone cannot diagnose… read more here.
Keywords: fumigatus; aspergillus fumigatus; scedosporium apiospermum; cytoskeletal alteration ... See more keywords
Aspergillus fumigatus Induces the Release of IL-8 and MCP-1 by Activating Nuclear Transcription Through Dectin-1 and CR3 Receptors in Alveolar Epithelial Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Current microbiology"
DOI: 10.1007/s00284-021-02534-5
Abstract: Invasive pulmonary aspergillosis induced by the pathogenic fungus Aspergillus fumigatus is one of the common fatal complications in immunocompromised patients. Lung epithelial cells play an important role in host immune defense against A. fumigatus. However,… read more here.
Keywords: aspergillus fumigatus; epithelial cells; cr3 receptors; dectin ... See more keywords
Fungal infection monitoring on corneal epithelium ex vivo model and its collection over polyethersulfone membrane for detecting Candida albicans and Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2025 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-025-00820-8
Abstract: In this paper we report a human ex vivo model of Aspergillus fumigatus and Candida albicans infection of the cornea. We demonstrate the ability to monitor fungal growth on the cornea through optical and immunofluorescence… read more here.
Keywords: vivo model; candida albicans; corneal; aspergillus fumigatus ... See more keywords
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01367-x
Abstract: Fungal keratitis (FK) is a keratopathy caused by pathogenic fungal infection. The aim of this work is to explore the role of thymic stromal lymphopoietin (TSLP) in FK. Human corneal epithelial cells (HCECs) were treated… read more here.
Keywords: aspergillus fumigatus; tslp; treatment; thp macrophages ... See more keywords
Azole Resistance in Veterinary Clinical Aspergillus fumigatus Isolates in the Netherlands
Sign Up to like & getrecommendations! Published in 2024 at "Mycopathologia"
DOI: 10.1007/s11046-024-00850-5
Abstract: Aspergillus fumigatus is a saprophytic fungal pathogen that causes opportunistic infections in animals and humans. Azole resistance has been reported globally in human A. fumigatus isolates, but the prevalence of resistance in isolates from animals… read more here.
Keywords: resistance; azole resistance; azole resistant; aspergillus fumigatus ... See more keywords
Trends of Azole-Resistant Aspergillus Fumigatus Susceptibility Over 12 Years from a German ECMM Excellence Center
Sign Up to like & getrecommendations! Published in 2025 at "Mycopathologia"
DOI: 10.1007/s11046-025-00941-x
Abstract: Numbers of infections with azole-resistant Aspergillus fumigatus (ARAf) were rising in the last decades. We assessed ARAf susceptibility trends towards five antifungal agents (amphotericin B (AMB), itraconazole (ITR), voriconazole (VCZ), olorofim (OLO) and manogepix (MGX))… read more here.
Keywords: resistance; years german; excellence center; azole resistant ... See more keywords