Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Natural Products"
DOI: 10.1021/acs.jnatprod.2c00954
Abstract: Emerging fungal infections require new, more efficient antifungal agents and therapies. AFP, a protein from Aspergillus giganteus with four disulfide bonds, is a promising candidate because it selectively inhibits the growth of filamentous fungi. In… read more here.
Keywords: disulfide; aspergillus giganteus; four disulfide; synthesis ... See more keywords
Fungal Infections as an Uprising Threat to Human Health: Chemosensitization of Fungal Pathogens With AFP From Aspergillus giganteus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.887971
Abstract: Occurrence and intensity of systemic invasive fungal infections have significantly risen in recent decades with large amount of mortality and morbidity rates at global level. Treatment therapy lies on the current antifungal interventions and are… read more here.
Keywords: chemosensitization fungal; aspergillus giganteus; antifungal drugs; resistance ... See more keywords