Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-017-1323-4
Abstract: BackgroundAspirin exerts side effects within the gastrointestinal tract. Hydrogen sulfide (H2S) and carbon monoxide (CO) have been implicated in gastroprotection but the mechanism of beneficial action of these gaseous mediators against aspirin-induced damage has not been… read more here.
Keywords: aspirin induced; afferent sensory; nitric oxide; gastroprotection ... See more keywords
MiR-877-5p targets PDK-1 to promote aspirin-induced apoptosis in gastric mucosal cells.
Sign Up to like & getrecommendations! Published in 2021 at "Die Pharmazie"
DOI: 10.1691/ph.2021.0926
Abstract: This study aimed to investigate the role of miR-877-5p in aspirin-induced gastric mucosal injury. MiRNA microarray analysis was performed using paired gastric mucosal samples to find differentially expressed miRNAs. miR-877-5p was selected for subsequent analyses.… read more here.
Keywords: ges cells; aspirin induced; mir 877; apoptosis ... See more keywords
Myopenic Obesity Determined by Fat Mass Percentage Predicts Risk of Aspirin-Induced Bleeding in Chinese Older Adults.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical interventions in aging"
DOI: 10.2147/cia.s405559
Abstract: Background Body mass index (BMI) correlates with aspirin-induced bleeding risk. However, skeletal muscle mass (SMM) loss and fat gain commonly occur with aging, making BMI not a reasonable marker of bleeding risk in older individuals.… read more here.
Keywords: aspirin induced; induced bleeding; risk; obesity ... See more keywords
Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s351100
Abstract: Purpose Gastric injury is a major issue for long-term administration of aspirin. In this work, we tried to explore the possibility of using BLG to alleviate aspirin-induced gastric injury, because of excellent abilities of BLG… read more here.
Keywords: aspirin induced; blg; gastric injury; induced gastric ... See more keywords
Gene Polymorphism of Aspirin-Induced Urticaria in Children With Kawasaki Disease
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DOI: 10.3389/fped.2019.00505
Abstract: Objective: To investigate the distribution of the single nucleotide polymorphism (SNP) of LTC4S A-444C in children with Kawasaki disease in northern China and determine whether LTC4S A-444C SNP is associated with aspirin-induced urticaria (AIU). Methods:… read more here.
Keywords: children kawasaki; aspirin induced; aiu genotypes; kawasaki disease ... See more keywords
Inhibition of Aspirin-Induced Gastrointestinal Injury: Systematic Review and Network Meta-Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.730681
Abstract: Background: Administration of aspirin has the potential for significant side effects of gastrointestinal (GI) injury mainly caused by gastric acid stimulation, especially in long-term users or users with original gastrointestinal diseases. The debate on the… read more here.
Keywords: aspirin induced; analysis; gastrointestinal injury; network meta ... See more keywords
Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020549
Abstract: Acid-reducing agents are commonly used for the prevention of aspirin-induced gastrointestinal complications such as peptic ulcers. As a novel potassium-competitive acid blocker, fexuprazan is expected to prevent aspirin-induced gastrointestinal complications. This randomized, open-label study aimed… read more here.
Keywords: fexuprazan; aspirin induced; pharmacodynamic pharmacokinetic; novel potassium ... See more keywords