A High-Throughput Assay to Identify Allosteric Inhibitors of the PLC-γ Isozymes Operating at Membranes.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00511
Abstract: The two phospholipase C-γ (PLC-γ) isozymes are major signaling hubs and emerging therapeutic targets for various diseases, yet there are no selective inhibitors for these enzymes. We have developed a high-throughput, liposome-based assay that features… read more here.
Keywords: assay identify; plc isozymes; allosteric inhibitors; throughput assay ... See more keywords
NOVEL FLOW-BASED ASSAY TO IDENTIFY ALLOSPECIFIC T CELLS IN TRANSPLANTATION STUDY
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/01.tp.0000698992.89779.6c
Abstract: Naoki Tanimine, Bryna E. Burrell, Jorge Pardo, Charles Rickert, Kang Mi Lee, Kevin Deng, Noel Feeney, Christian Lequern, James F. Markmann Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan; Department of Surgery, Center… read more here.
Keywords: identify allospecific; assay identify; novel flow; flow based ... See more keywords
An accurate genetic assay to identify human neutrophil antigen 2 deficiency
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DOI: 10.1111/tme.12936
Abstract: We aimed to develop accurate and user‐friendly genetic assays to identify the inherited neutrophil antigen‐2 (HNA‐2) deficiency in humans. read more here.
Keywords: genetic assay; neutrophil antigen; accurate genetic; assay identify ... See more keywords