An In Sitro Assay to Predict Primary Resistance to PD-1 Blockade.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2021.01.006
Abstract: Immune check point inhibition (ICI) is a paradigm shift in oncology, but most patients treated with ICI will not respond to treatment. Thus, the need for predictive biomarkers for ICI is high. Dubuisson and colleagues… read more here.
Keywords: resistance blockade; predict primary; primary resistance; assay predict ... See more keywords
Development and Validation of a Next-Generation Sequencing–Based Multigene Assay to Predict the Prognosis of Estrogen Receptor–Positive, HER2-Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-20-2107
Abstract: Purpose: Multigene assays provide useful prognostic information regarding hormone receptor (HR)-positive breast cancer. Next-generation sequencing (NGS)-based platforms have numerous advantages including reproducibility and adaptability in local laboratories. This study aimed to develop and validate an… read more here.
Keywords: assay predict; cancer; breast cancer; based multigene ... See more keywords
Pharmacogenomic blood-based assay to predict chemotherapy response and survival in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.4_suppl.738
Abstract: 738Background: Pancreatic adenocarcinoma (PDAC) is for most patients a refractory disease. Modern cytotoxic chemotherapeutics (C) are not yet optimal for inducing responses and extending life. We a... read more here.
Keywords: chemotherapy response; pharmacogenomic blood; assay predict; blood based ... See more keywords
Fast assay to predict multipotent mesenchymal stromal cell replicative senescence dynamics.
Sign Up to like & getrecommendations! Published in 2022 at "BioTechniques"
DOI: 10.2144/btn-2021-0087
Abstract: The major obstacle to the application of mesenchymal stromal cells (MSCs) in regenerative medicine is the expansion of the donor-derived cells in vitro to obtain high cell numbers in the shortest possible time. However, MSCs gradually undergo replicative… read more here.
Keywords: cell; mesenchymal stromal; fast assay; senescence ... See more keywords