The binacle (binding and cleavage) assay for in vitro determination of botulinum neurotoxin activity
Sign Up to like & getrecommendations! Published in 2018 at "Toxicon"
DOI: 10.1016/j.toxicon.2018.11.026
Abstract: Principle of the BINACLE assay. (I.) BoNT molecules (grey) bind to immobilized receptors (blue and red) via their H-chains. Then the L-chains are released by reduction of the disulfide bonds. (II.) The supernatant with the… read more here.
Keywords: binding cleavage; cleavage; binacle binding; binacle ... See more keywords