Articles with "assays alkbh5" as a keyword



Development of formaldehyde dehydrogenase‐coupled assay and antibody‐based assays for ALKBH5 activity evaluation

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Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.09.018

Abstract: &NA; N6‐methyladenosine (m6A) is the most prevalent internal modification of eukaryotic messenger RNA (mRNA). Until now, two RNA demethylases have been identified, including FTO (fat mass and obesity‐associated protein) and ALKBH5 (&agr;‐ketoglutarate‐dependent dioxygenase alkB homologue… read more here.

Keywords: antibody based; assays alkbh5; dehydrogenase coupled; formaldehyde dehydrogenase ... See more keywords