Defining the relative performance of isothermal assays that can be used for rapid and sensitive detection of foot-and-mouth disease virus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2017.08.013
Abstract: Highlights • Isothermal assays representative of RT-LAMP and RT-RPA were compared against rRT-PCR.• Nine sample preparation methods were evaluated across all assays.• RT-LAMP can detect FMDV in multiple sample types using simple preparation techniques.• RT-LAMP… read more here.
Keywords: detection; defining relative; assays used; isothermal assays ... See more keywords
On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.09.022
Abstract: ABSTRACT The US EPA is charged with screening chemicals for their ability to be endocrine disruptors through interaction with the estrogen, androgen and thyroid axes. The agency is exploring the use of high‐throughput in vitro… read more here.
Keywords: selecting minimal; vitro; vitro assays; set vitro ... See more keywords
Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression
Sign Up to like & getrecommendations! Published in 2023 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2023-006808
Abstract: Background Chordoma is an extremely rare, locally aggressive malignant bone tumor originating from undifferentiated embryonic remnants. There are no effective therapeutic strategies for chordoma. Herein, we aimed to explore cellular interactions within the chordoma immune… read more here.
Keywords: chordoma; immune microenvironment; malignant progression; tumor ... See more keywords
Assays Used for Discovering Small Molecule Inhibitors of YAP Activity in Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14041029
Abstract: Simple Summary Cancer is a disease in which cells grow in an uncontrolled manner. This can be due to excessive cell proliferation or reduced cell death or a combination of the two. The Hippo signaling… read more here.
Keywords: small molecule; cell; yap activity; activity ... See more keywords