Using minimalist self‐assembling peptides as hierarchical scaffolds to stabilise growth factors and promote stem cell integration in the injured brain
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2582
Abstract: Neurotrophic growth factors are effective in slowing progressive degeneration and/or promoting neural repair through the support of residual host and/or transplanted neurons. However, limitations including short half‐life and enzyme susceptibility of growth factors highlight the… read more here.
Keywords: growth; assembling peptides; self assembling; delivery ... See more keywords
Supramolecular Self-Assembling Peptides to Deliver Bone Morphogenetic Proteins for Skeletal Regeneration.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115565
Abstract: Recombinant human bone morphogenetic proteins (BMPs) have shown clinical success in promoting bone healing, but they are also associated with unwanted side effects. The development of improved BMP carriers that can retain BMP at the… read more here.
Keywords: assembling peptides; self assembling; morphogenetic proteins; regeneration ... See more keywords
Short Peptides Derived from a Block Copolymer-like Barnacle Cement Protein Self-Assembled into Diverse Supramolecular Structures.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00031
Abstract: Peptides capable of self-assembling into different supramolecular structures have potential applications in a variety of areas. The biomimetic molecular design offers an important avenue to discover novel self-assembling peptides. Despite this, a lot of biomimetic… read more here.
Keywords: self assembly; supramolecular structures; assembling peptides; self assembling ... See more keywords
Self-assembling peptides cross-linked with genipin: resilient hydrogels and self-standing electrospun scaffolds for tissue engineering applications.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c8bm00825f
Abstract: Self-assembling peptides (SAPs) are synthetic bioinspired biomaterials that can be feasibly multi-functionalized for applications in surgery, drug delivery, optics and tissue engineering (TE). Despite their promising biocompatibility and biomimetic properties, they have never been considered… read more here.
Keywords: assembling peptides; self assembling; cross linked; self standing ... See more keywords
Self-assembling peptides-based nano-cargos for targeted chemotherapy and immunotherapy of tumors: recent developments, challenges, and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2058647
Abstract: Abstract Self-assembling peptides (SAPs) have enormous potential in medical and biological applications, particularly noninvasive tumor therapy. SAPs self-assembly is governed by multiple non-covalent interactions and results in the formation of a variety of morphological features.… read more here.
Keywords: based nano; nano cargos; self assembling; tumor ... See more keywords
Discovery and design of self-assembling peptides
Sign Up to like & getrecommendations! Published in 2017 at "Interface Focus"
DOI: 10.1098/rsfs.2017.0028
Abstract: Peptides are ubiquitous in nature and useful in many fields, from agriculture as pesticides, in medicine as antibacterial and antifungal drugs founded in the innate immune systems, to medicinal chemistry as hormones. However, the concept… read more here.
Keywords: discovery design; medicine; assembling peptides; self assembling ... See more keywords
Use of Self-Assembling Peptides to Enhance Stem Cell Function for Therapeutic Angiogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells International"
DOI: 10.1155/2018/4162075
Abstract: The use of nanomaterials for biomedical applications has become a promising field in regenerative medicine. Self-assembling peptides (SAPs) have been proposed as a good candidate because they are able to self-assemble into stable hydrogels and… read more here.
Keywords: assembling peptides; self assembling; angiogenesis; use ... See more keywords
Advancements in self-assembling peptides: Bridging gaps in 3D cell culture and electronic device fabrication
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282241240139
Abstract: Self-assembling peptides (SAPs) show promise in creating synthetic microenvironments that regulate cellular function and tissue repair. Also, the precise π-π interactions and hydrogen bonding within self-assembled peptide structures enable the creation of quantum confined structures,… read more here.
Keywords: cell culture; self assembling; peptides bridging; culture ... See more keywords
Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1105157
Abstract: Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their… read more here.
Keywords: long term; human pancreatic; assembling peptides; self assembling ... See more keywords
Self-assembling peptides for sciatic nerve regeneration: a review of conduit microenvironment modeling strategies in preclinical studies
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2025.1637189
Abstract: Effective nerve conduits development remains a significant challenge in regenerative medicine, with the potential to greatly improve patients’ quality of life in case of peripheral nerve injury. To date, several tubular devices have been introduced… read more here.
Keywords: nerve; conduit; nerve regeneration; self assembling ... See more keywords
Supramolecular Nanomedicines of In-Situ Self-Assembling Peptides
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.815551
Abstract: Nanomedicines provide distinct clinical advantages over traditional monomolecular therapeutic and diagnostic agents. Supramolecular nanomedicines made from in-situ self-assembling peptides have emerged as a promising strategy in designing and fabricating nanomedicines. In-situ self-assambly (SA) allows the… read more here.
Keywords: situ self; assembling peptides; self assembling; supramolecular nanomedicines ... See more keywords