novoBreak: local assembly for breakpoint detection in cancer genomes
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DOI: 10.1038/nmeth.4084
Abstract: We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data. novoBreak consistently outperformed existing algorithms on real cancer genome data and on synthetic tumors in… read more here.
Keywords: assembly; local assembly; assembly breakpoint; novobreak local ... See more keywords