5-Aminothiophene-2,4-dicarboxamide analogues as hepatitis B virus capsid assembly effectors.
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DOI: 10.1016/j.ejmech.2018.12.047
Abstract: Chronic hepatitis B virus (HBV) infection represents a major health threat. Current FDA-approved drugs do not cure HBV. Targeting HBV core protein (Cp) provides an attractive approach toward HBV inhibition and possibly infection cure. We… read more here.
Keywords: capsid assembly; chemistry; hepatitis virus; assembly effectors ... See more keywords