Evolution, structure and membrane association of NDUFAF6, an assembly factor for NADH:ubiquinone oxidoreductase (Complex I).
Sign Up to like & getrecommendations! Published in 2017 at "Mitochondrion"
DOI: 10.1016/j.mito.2017.04.005
Abstract: The NADH:ubiquinone oxidoreductase (complex I) is the largest member of the mitochondrial respiratory chain. Its FMN cofactor accepts two electrons from NADH and transfers them to ubiquinone via a chain of iron-sulphur centers. A central… read more here.
Keywords: oxidoreductase complex; ubiquinone oxidoreductase; assembly factor; nadh ubiquinone ... See more keywords
Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115566119
Abstract: Significance Mitochondria are double-membraned eukaryotic organelles that house the proteins required for generation of ATP, the energy currency of cells. ATP generation within mitochondria is performed by five multisubunit complexes (complexes I to V), the… read more here.
Keywords: mitochondrial disease; sideroflexin complex; factor interacts; interacts mcia ... See more keywords
Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e21-03-0143
Abstract: Assembly of the dimeric complex III (CIII2) in the mitochondrial inner membrane is an intricate process, in which several accessory proteins are involved as assembly factors. Despite numerous studies, this process is yet to be… read more here.
Keywords: ovarian carcinoma; complex iii; carcinoma immunoreactive; immunoreactive antigen ... See more keywords
Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development.
Sign Up to like & getrecommendations! Published in 2023 at "Blood advances"
DOI: 10.1182/bloodadvances.2022009438
Abstract: Acute myeloid leukemia (AML) is an aggressive blood cancer that stems from the rapid expansion of immature leukemic blasts in the bone marrow. Mutations in epigenetic factors represent the largest category of genetic drivers of… read more here.
Keywords: aml; repression; chromatin assembly; factor chaf1b ... See more keywords
Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2.
Sign Up to like & getrecommendations! Published in 2017 at "RNA"
DOI: 10.1261/rna.059881.116
Abstract: A seven-subunit Sm protein ring assembles around specific U-rich RNA segments of the U1, U2, U4, and U5 snRNPs that direct pre-mRNA splicing. Using human snRNP crystal structures to guide mutagenesis in Saccharomyces cerevisiae, we… read more here.
Keywords: gemin2; brr1; assembly factor; factor brr1 ... See more keywords
Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.3892/or.2022.8319
Abstract: The aim of the present study was to investigate the expression of ribosome assembly factor partner of NOB1 homolog (PNO1) and its association with the progression of breast cancer (BC) in patients, as well as… read more here.
Keywords: ribosome assembly; progression; expression; breast cancer ... See more keywords