Modeling and Designing Particle-Regulated Amyloid-like Assembly of Synthetic Polypeptides in Aqueous Solution.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01230
Abstract: In cells, actin and tubulin polymerization is regulated by nucleation factors, which promote the nucleation and subsequent growth of protein filaments in a controlled manner. Mimicking this natural mechanism to control the supramolecular polymerization of… read more here.
Keywords: polymerization; amyloid like; nucleation factors; supramolecular polymerization ... See more keywords
Bottom-Up Assembly of Synthetic Cells with a DNA Cytoskeleton.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10703
Abstract: Cytoskeletal elements, like actin and myosin, have been reconstituted inside lipid vesicles toward the vision to reconstruct cells from the bottom up. Here, we realize the de novo assembly of entirely artificial DNA-based cytoskeletons with… read more here.
Keywords: assembly synthetic; cells dna; dna; bottom assembly ... See more keywords
Controllable assembly of synthetic constructs with programmable ternary DNA interaction
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac478
Abstract: Abstract Compared with the dual binding components in a binary interaction, the third component of a ternary interaction often serves as modulator or regulator in biochemical processes. Here, we presented a programmable ternary interaction strategy… read more here.
Keywords: interaction; dna; controllable assembly; programmable ternary ... See more keywords