Articles with "assessing developmental" as a keyword



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Allogeneic murine pregnancy models for assessing the developmental effects of immune-stimulating antibodies: Challenges in reproducibility.

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Published in 2019 at "Birth defects research"

DOI: 10.1002/bdr2.1542

Abstract: Literature suggests that murine allogeneic pregnancy models are an alternative approach for evaluating the developmental toxicity of immune-stimulating agents. In this study, multiple syngeneic and allogeneic murine pregnancy models were used to assess the potential… read more here.

Keywords: murine pregnancy; pregnancy; allogeneic murine; immune stimulating ... See more keywords
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Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22041908

Abstract: With increasing global health threats has come an urgent need to rapidly develop and deploy safe and effective therapies. A common practice to fast track clinical adoption of compounds for new indications is to repurpose… read more here.

Keywords: derived platforms; rapidly assessing; assessing developmental; ipsc derived ... See more keywords