Articles with "assessment carboxylesterase" as a keyword



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A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms

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Published in 2017 at "Drug Metabolism and Disposition"

DOI: 10.1124/dmd.117.077669

Abstract: Carboxylesterase 1 (CES1) is the predominant human hepatic hydrolase responsible for the metabolism of many clinically important medications. CES1 expression and activity vary markedly among individuals; and genetic variation is a major contributing factor to… read more here.

Keywords: functional assessment; assessment carboxylesterase; carboxylesterase; ces1 ... See more keywords