The assessment of drug safety for the fetus
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Pharmacy"
DOI: 10.1007/s11096-020-01132-y
Abstract: Long standing concerns regarding the use of medications during pregnancy and their unknown effects on fetal development and child health suggests the need for modified study methods regarding the establishment of drug safety for the… read more here.
Keywords: drug safety; assessment drug; safety fetus;
A nephron model for study of drug-induced acute kidney injury and assessment of drug-induced nephrotoxicity.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.11.010
Abstract: In this study, we developed a multilayer microfluidic device to simulate nephron, which was formed by "glomerulus", "Bowman's capsule", "proximal tubular lumen" and "peritubular capillary". In this microdevice, artificial renal blood flow was circulating and… read more here.
Keywords: assessment drug; induced nephrotoxicity; drug induced; drug ... See more keywords
Assessment of drug-drug interactions of CC-90001, a potent and selective inhibitor of c-Jun N-terminal kinase
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2027553
Abstract: Abstract CC-90001 is predominantly metabolised via glucuronidation, while oxidative metabolism is a minor pathway in human hepatocytes and liver microsomes. In vitro, CC-90001 glucuronidation was catalysed by UGT1A9, UGT1A4, and UGT1A1, while oxidative metabolism was… read more here.
Keywords: drug drug; drug; inhibitor; interactions 90001 ... See more keywords
Critical assessment of AI in drug discovery
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2021.1915982
Abstract: ABSTRACT Introduction: Artificial Intelligence (AI) has become a component of our everyday lives, with applications ranging from recommendations on what to buy to the analysis of radiology images. Many of the techniques originally developed for… read more here.
Keywords: assessment drug; discovery critical; drug; critical assessment ... See more keywords
Assessment of Drug Release Kinetics and Quality of Naproxen Generic Tablets in Bangladesh
Sign Up to like & getrecommendations! Published in 2021 at "Dissolution Technologies"
DOI: 10.14227/dt280221p30
Abstract: The present study aimed to compare the in vitro equivalence of different generic tablets of naproxen available with the reference brand in the Bangladesh pharmaceutical market. As naproxen belongs to the biopharmaceutics classification system (BCS)… read more here.
Keywords: reference brand; quality; assessment drug; dissolution ... See more keywords
Assessment of Drug Flow Rate in Skin Cancer Therapy for Enhancing the Drug Delivery System.
Sign Up to like & getrecommendations! Published in 2020 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202020180985
Abstract: The major impact in the clinical field is the harm posed by cancer. One most common type of cancer occurs in the skin. Though the conventionally existing modalities are successful in some cases, there is… read more here.
Keywords: flow rate; assessment drug; drug; cancer ... See more keywords
The Assessment of Drug Use Pattern Using WHO Prescribing Indicators.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nepal Health Research Council"
DOI: 10.33314/jnhrc.v16i3.1208
Abstract: BACKGROUND In order to promote rational drug use in developing countries, assessment of drug use pattern using the World Health Organization drug use indicators is important. The aim of this study was to assess the… read more here.
Keywords: pattern using; assessment drug; drug use; drug ... See more keywords