Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.10.073
Abstract: A series of 6-substituted azaanthraquinone derivatives have been designed, synthesized, and their anti-inflammatory activities, antiaggregation effects on β-amyloid proteins, anticholinesterase and neuroprotective activity were tested. The new derivatives strongly suppressed NO and iNOS production and… read more here.
Keywords: novel azaanthraquinone; aggregation; derivatives potent; potent multi ... See more keywords
Experimental assessment of novel PAX6 splicing mutations in two Chinese families with aniridia.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.07.073
Abstract: Aniridia is a rare, congenital ocular disorder caused by the mutations of the paired box gene-6 (PAX6) (OMIM 607108), which encodes a highly conserved transcriptional regulator. In order to investigate the clinical characterizations and genetic… read more here.
Keywords: pax6; two chinese; novel pax6; experimental assessment ... See more keywords
Synthesis and biological assessment of novel cyanopyridine derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1616096
Abstract: Abstract New pyridine derivatives bearing p-dimethyl amino phenyl and p-bromophenyl moieties at position-4 and 6 have been prepared. The behavior of pyridone derivative 2 toward ethyl chloroacetate followed by hydrazine hydrate gave pyridinyl acetohydrazide derivative… read more here.
Keywords: novel cyanopyridine; assessment novel; synthesis biological; cyanopyridine derivatives ... See more keywords
Experimental Assessment of a Novel Hybrid Scheme for Quantitative GPR Imaging
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Geoscience and Remote Sensing Letters"
DOI: 10.1109/lgrs.2021.3121808
Abstract: A hybrid inversion procedure for subsoil prospecting by ground-penetrating radar (GPR) measurements is proposed and experimentally validated in this letter. The approach integrates the benefits of qualitative beamforming in an adaptive multifrequency (MF) inexact-Newton scheme… read more here.
Keywords: novel hybrid; gpr; hybrid scheme; experimental assessment ... See more keywords
An in vitro assessment of novel chitosan/bimetallic PtAu nanocomposites as delivery vehicles for doxorubicin.
Sign Up to like & getrecommendations! Published in 2017 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0228
Abstract: AIM To synthesize and functionalize platinum (core)-gold (shell) bimetallic nanoparticles (PtAuBNps) with chitosan and doxorubicin to display favorable pharmacokinetics, biodegradability, biological activity and safety in vitro. MATERIALS & METHODS PtAuBNps and their drug nanocomposites were… read more here.
Keywords: novel chitosan; chitosan bimetallic; bimetallic ptau; delivery ... See more keywords
A taxonomic assessment of novel and remarkable fungal species in Didymosphaeriaceae (Pleosporales, Dothideomycetes) from plant litter
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1016285
Abstract: Fungal taxonomy has a long history and changed significantly in the last few decades. Most recent studies have witnessed morphology combined with DNA-based molecular analyses as the main research tool for fungal species identification. During… read more here.
Keywords: fungal species; taxonomic assessment; assessment novel; plant litter ... See more keywords
Assessment of a Novel Instrument Measuring Perceived Physical Education Teachers’ In-Class Skills
Sign Up to like & getrecommendations! Published in 2023 at "Behavioral Sciences"
DOI: 10.3390/bs13010042
Abstract: Physical Education (PE) teachers’ professional and personal skills may not only affect the quality of the teaching-learning processes in PE, but also individuals’ future active/inactive behaviors. The aim of this study is to examine the… read more here.
Keywords: education teachers; instrument; novel instrument; physical education ... See more keywords