Synthesis and antiproliferative assessments of new derivatives of isothiazolo[3,4-d]pyrimidine
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DOI: 10.1080/17415993.2020.1841192
Abstract: ABSTRACT Various derivatives of 5-aryl-4-imino-3-(phenylamino)-4,5-dihydroisothiazolo[3,4-d]pyrimidines (3a-f) were synthesized. The synthesis has been done through treatment of 3-amino-4-cyano-5-(phenylamino)isothiazole with various aryl isothiocyanates. The isothiazole skeleton was obtained by the reaction of malononitrile and phenyl isothiocyanate followed… read more here.
Keywords: antiproliferative assessments; new derivatives; assessments new; derivatives isothiazolo ... See more keywords