Automated assignment of methyl NMR spectra from large proteins.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in nuclear magnetic resonance spectroscopy"
DOI: 10.1016/j.pnmrs.2020.04.001
Abstract: As structural biology trends towards larger and more complex biomolecular targets, a detailed understanding of their interactions and underlying structures and dynamics is required. The development of methyl-TROSY has enabled NMR spectroscopy to provide atomic-resolution… read more here.
Keywords: methyl; methyl nmr; nmr spectra; assignment methyl ... See more keywords
NMR Assignment of Methyl Groups in Immobilized Proteins Using Multiple-Bond 13C Homonuclear Transfers, Proton Detection, and Very Fast MAS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.828785
Abstract: In nuclear magnetic resonance spectroscopy of proteins, methyl protons play a particular role as extremely sensitive reporters on dynamics, allosteric effects, and protein–protein interactions, accessible even in high-molecular-weight systems approaching 1 MDa. The notorious issue… read more here.
Keywords: methyl groups; spectroscopy; assignment methyl; nmr assignment ... See more keywords