Computational methods to assist in the discovery of pharmacological chaperones for rare diseases
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DOI: 10.1093/bib/bbac198
Abstract: Pharmacological chaperones are chemical compounds able to bind proteins and stabilize them against denaturation and following degradation. Some pharmacological chaperones have been approved, or are under investigation, for the treatment of rare inborn errors of… read more here.
Keywords: discovery pharmacological; assist discovery; pharmacological chaperones; computational methods ... See more keywords
Computational modeling to assist in the discovery of supramolecular materials
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DOI: 10.1111/nyas.14913
Abstract: Computational modeling is increasingly used to assist in the discovery of supramolecular materials. Supramolecular materials are typically primarily built from organic components that are selfâassembled through noncovalent bonding and have potential applications, including in selective… read more here.
Keywords: assist discovery; supramolecular materials; discovery supramolecular; prediction ... See more keywords