Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission.
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DOI: 10.1242/jcs.260612
Abstract: Mitochondrial homeostasis requires a dynamic balance of fission and fusion. The actin cytoskeleton promotes fission; we find that the mitochondrially-localized myosin, Myosin 19 (Myo19), is integral to this process. Myo19 knock-down induces mitochondrial elongation, while… read more here.
Keywords: myo19; endoplasmic reticulum; fission; myo19 tethers ... See more keywords