Activated mast cells in skeletal muscle can be a potential mediator for cancer‐associated cachexia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12714
Abstract: Eighty per cent of United States advanced cancer patients faces a worsened prognosis due to cancer‐associated cachexia. Inflammation is one driver of muscle atrophy in cachexia, and skeletal muscle‐resident immune cells could be a source… read more here.
Keywords: skeletal muscle; associated cachexia; muscle; mast cells ... See more keywords
Nanoparticle-Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer-Associated Cachexia.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204436
Abstract: This study presents the first messenger RNA (mRNA) therapy for metastatic ovarian cancer and cachexia-induced muscle wasting based on lipid nanoparticles that deliver follistatin (FST) mRNA predominantly to cancer clusters following intraperitoneal administration. The secreted… read more here.
Keywords: messenger rna; ovarian cancer; therapy; associated cachexia ... See more keywords
Diet-related interventions for cancer-associated cachexia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03592-9
Abstract: Cancer-associated cachexia is a common condition in patients with advanced cancer, and is associated with extreme and involuntary weight loss and irreversible muscle wasting. Despite its high morbidity and mortality, there is no known treatment… read more here.
Keywords: therapy; associated cachexia; diet related; related interventions ... See more keywords
Combating chronic kidney disease-associated cachexia: A literature review of recent therapeutic approaches
Sign Up to like & getrecommendations! Published in 2025 at "BMC Nephrology"
DOI: 10.1186/s12882-025-04057-8
Abstract: In 2008, the Society on Sarcopenia, Cachexia, and Wasting Disorders introduced a generic definition for all types of cachexia: “a complex metabolic syndrome associated with the underlying illness characterized by a loss of muscle, with… read more here.
Keywords: associated cachexia; disease; kidney disease; chronic kidney ... See more keywords
Association of lung cancer-associated cachexia with the metastatic spread to pleura.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.12095
Abstract: 12095 Background: Cancer-associated cachexia (CAC), a major contributor to mortality in patients with non-small cell lung cancer (NSCLC), is characterized by alterations in body composition. Here, we explore the associations between body composition changes and… read more here.
Keywords: cancer; lung; lung cancer; associated cachexia ... See more keywords
Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22243
Abstract: Cancer is commonly associated with cachexia, a paraneoplastic syndrome characterized by body weight loss, muscle wasting, adipose tissue atrophy and inflammation. Chronic alcohol consumption increases the risk of multiple types of cancer, and enhances cancer-associated… read more here.
Keywords: associated cachexia; muscle; cancer; cancer associated ... See more keywords
Emerging Treatment Options For Cancer-Associated Cachexia: A Literature Review
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s196802
Abstract: Abstract Cachexia is a disease that has been recognized since antiquity; however, research in this area has recently increased. Promising new agents, including anamorelin hydrochloride, have been tested in large randomized controlled studies, and multidrug… read more here.
Keywords: literature; review; treatment; cancer associated ... See more keywords
Abnormal lipid metabolism in cancer-associated cachexia and potential therapy strategy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1123567
Abstract: Cancer-associated cachexia (CAC) is a major characteristic of advanced cancer, associates with almost all types of cancer. Recent studies have found that lipopenia is an important feature of CAC, and it even occurs earlier than… read more here.
Keywords: cac; adipose tissue; associated cachexia; cancer associated ... See more keywords
Redox Signaling in Chronic Kidney Disease-Associated Cachexia
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12040945
Abstract: Redox signaling alterations contribute to chronic kidney disease (CKD)-associated cachexia. This review aims to summarize studies about redox pathophysiology in CKD-associated cachexia and muscle wasting and to discuss potential therapeutic approaches based on antioxidant and… read more here.
Keywords: chronic kidney; associated cachexia; kidney disease; ckd associated ... See more keywords
Immune System Disorder and Cancer-Associated Cachexia
Sign Up to like & getrecommendations! Published in 2024 at "Cancers"
DOI: 10.3390/cancers16091709
Abstract: Simple Summary Cancer-associated cachexia (CAC) is a serious condition wherein people with cancer lose muscle and fat, even with proper nutrition. It leads to weakness and can make treatment less effective. This review looks at… read more here.
Keywords: cancer; associated cachexia; cac; immune system ... See more keywords