Articles with "associated cdk4" as a keyword



Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system

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Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1558128

Abstract: Background Despite the unprecedented advancement of cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) in the treatment paradigm for hormone-dependent breast cancer, reports of cardiovascular adverse events (CVAEs) in both pivotal trials and real-world settings have… read more here.

Keywords: fda adverse; associated cdk4; cvaes; real world ... See more keywords