Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2054205
Abstract: ABSTRACT Terpinen-4-ol (T4O), a compound isolated from the seeds of turmeric, has exhibited anti-malignancy, anti-aging, and anti-inflammatory properties in previous studies. However, the specific effects and molecular mechanisms of T4O on pancreatic cancer (PC) cells… read more here.
Keywords: rho associated; proliferation; pancreatic cancer; coiled coil ... See more keywords
Rho‐associated, coiled‐coil‐containing protein kinase 1 as a new player in the regulation of hepatic lipogenesis
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DOI: 10.1111/jdi.13051
Abstract: Rho‐associated, coiled‐coil‐containing protein kinase 1 might have applications as a potential therapeutic target for the treatment of non‐alcoholic fatty liver disease. read more here.
Keywords: rho associated; associated coiled; protein kinase; coiled coil ... See more keywords
Involvement of Rho-associated coiled-coil kinase signaling inhibition in TGF-β1/Smad2, 3 signal transduction in vitro.
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DOI: 10.18240/ijo.2017.12.03
Abstract: AIM To research the effect of Y-27632, a selective Rho-associated coiled-coil kinase (ROCK) inhibitor, on TGF-β1/Smad2, 3 signal transduction in ocular Tenon's capsule fibroblasts (OTFs). METHODS Primary ocular Tenon's capsule fibroblasts had been cultured in… read more here.
Keywords: tgf smad2; coil kinase; rho associated; tgf ... See more keywords