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Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32626
Abstract: Inflammation is currently considered a hallmark of cancer and plays a decisive role in different stages of tumorigenesis, including initiation, promotion, progression, metastasis and resistance to antitumor therapies. Colorectal cancer is a disease widely associated…
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Keywords:
colon;
associated colon;
colon cancer;
colitis associated ... See more keywords
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Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.050
Abstract: SUMMARY IL-10 functions as a suppressor of colitis and colitis-associated colon cancer, but it is also a risk locus associated with ulcerative colitis. The mechanism underlying the contrasting roles of IL-10 in inflammation and colon…
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Keywords:
dnmt3b;
colon;
associated colon;
colitis ... See more keywords
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Published in 2018 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aan4116
Abstract: The commonly used antimicrobial compound triclosan increases colonic inflammation and colon cancer in mice. Triclosan triggers inflammation Antimicrobials are ubiquitous in manufactured products beyond hand soap and exist in the environment as pollutants. Triclosan exposure…
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Keywords:
colonic inflammation;
inflammation;
colon;
associated colon ... See more keywords
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Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18061284
Abstract: Ulcerative colitis (UC) is defined as an idiopathic inflammatory disorder primarily involving the mucosa and submucosa of the colon. UC-associated colon cancers (also known as colitic cancers) develop through the inflammation–dysplasia sequence, which is a…
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Keywords:
colon;
associated colon;
expression;
ulcerative colitis ... See more keywords
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Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18091908
Abstract: We have previously reported alleviation of dextran sodium sulfate (DSS)-induced ulcerative colitis signs in phenethyl isothiocyanate (PEITC)-treated mice. Here we investigated chemoprotective activities of PEITC in mice with Azoxymethane-DSS induced colitis associated colon carcinogenesis. We…
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Keywords:
colon;
phenethyl isothiocyanate;
colitis;
associated colon ... See more keywords