Somatic mutation profiles as molecular classifiers of ulcerative colitis‐associated colorectal cancer
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Cancer"
DOI: 10.1002/ijc.33492
Abstract: Ulcerative colitis increases colorectal cancer risk by mechanisms that remain incompletely understood. We approached this question by determining the genetic and epigenetic profiles of colitis‐associated colorectal carcinomas (CA‐CRC). The findings were compared to Lynch syndrome… read more here.
Keywords: colorectal cancer; group; ulcerative colitis; colitis associated ... See more keywords
Endometriosis-associated colorectal carcinosarcoma: A case report and review of the literature☆
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2021.100696
Abstract: Highlights • Endometriosis associated intestinal tumors are rare, with 5 cases documented.• Endometriosis associated intestinal tumors might present like colorectal carcinoma.• Endometriosis associated intestinal Carcinoma is associated with poor prognosis. read more here.
Keywords: endometriosis; endometriosis associated; carcinosarcoma case; associated intestinal ... See more keywords
PUFA levels in erythrocyte membrane phospholipids are differentially associated with colorectal adenoma risk
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Nutrition"
DOI: 10.1017/s0007114517001490
Abstract: Abstract Dietary intake of PUFA has been associated with colorectal neoplasm risk; however, results from observational studies have been inconsistent. Most prior studies have utilised self-reported dietary measures to assess fatty acid exposure which might… read more here.
Keywords: pufa; risk; adenoma; erythrocyte membrane ... See more keywords
Dvl2 facilitates the coordination of NF-κB and Wnt signaling to promote colitis-associated colorectal progression.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer science"
DOI: 10.1111/cas.15206
Abstract: Colitis-associated colorectal cancer (CAC) arises due to prolonged inflammation and has distinct molecular events compared to sporadic colorectal cancer (CRC). Although inflammatory NF-κB signaling was activated by proinflammatory cytokines (such as TNFα) in early-stage of… read more here.
Keywords: wnt; facilitates coordination; colitis associated; associated colorectal ... See more keywords
Single probiotic supplement suppresses colitis‐associated colorectal tumorigenesis by modulating inflammatory development and microbial homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.14516
Abstract: Chronic inflammation is a major contributor to the initiation and progression of cancers. Lactobacillus helveticus NS8, which was originally separated from fermented koumiss, exhibited anti‐inflammatory functions in our prior studies. In this study, NS8 was… read more here.
Keywords: suppresses colitis; single probiotic; colitis associated; associated colorectal ... See more keywords
Intestinal epithelial glucocorticoid receptor promotes chronic inflammation-associated colorectal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "JCI insight"
DOI: 10.1172/jci.insight.151815
Abstract: Synthetic immunosuppressive glucocorticoids (GCs) are widely used to control inflammatory bowel disease (IBD). However, the impact of GC signaling on intestinal tumorigenesis remains controversial. Here, we report that intestinal epithelial glucocorticoid receptor (GR), but not… read more here.
Keywords: intestinal epithelial; inflammation associated; colorectal cancer; glucocorticoid ... See more keywords
Biomarkers for early detection of colitis-associated colorectal cancer - current concepts, future trends.
Sign Up to like & getrecommendations! Published in 2020 at "Current drug targets"
DOI: 10.2174/1389450121666200220123844
Abstract: Colitis-associated colorectal cancer (CAC) remains a critical complication of ulcerative colitis (UC) with mortality of approximately 15%, which makes early CAC diagnosis crucial. The current standard of surveillance, with repetitive colonoscopies and histological testing of… read more here.
Keywords: early detection; colorectal cancer; colitis associated; cancer ... See more keywords
Identifying neutrophil-associated subtypes in ulcerative colitis and confirming neutrophils promote colitis-associated colorectal cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1095098
Abstract: Background Ulcerative colitis (UC) is a chronic inflammatory disease of the intestinal mucosa, the incidence of which has increased worldwide. There is still a lack of clear understanding of the pathogenesis of ulcerative colitis that… read more here.
Keywords: colitis associated; colitis; colorectal cancer; neutrophil associated ... See more keywords
Huangqin Tang Interference With Colitis Associated Colorectal Cancer Through Regulation of Epithelial Mesenchymal Transition and Cell Cycle
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.837217
Abstract: Background: Although the exact molecular mechanisms of colitis-associated colorectal cancer are not fully understood, the chronic inflammation was positively correlated with tumorigenesis. The traditional Chinese medicine botanical formulation Huangqin Tang has significant anti-inflammatory effects. We… read more here.
Keywords: colitis associated; colorectal cancer; huangqin tang; associated colorectal ... See more keywords
Rumex japonicus Houtt. Extract Suppresses Colitis-Associated Colorectal Cancer by Regulating Inflammation and Tight-Junction Integrity in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.946909
Abstract: Irritable bowel disease (IBD), which results in an elevated risk of colitis-associated colorectal cancer (CAC), is characterized by inflammation and barrier disruption of the gut. The genus Rumex has anti-oxidative and anti-inflammatory effects, and the… read more here.
Keywords: inflammation; rumex japonicus; colitis associated; colorectal cancer ... See more keywords
Effects of Cheonggukjang (Fermented Soybean) on the Development of Colitis-Associated Colorectal Cancer in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12020383
Abstract: Colorectal cancer (CRC) is the third most common type of cancer and is caused by multiple factors. Chronic inflammation, known to cause inflammatory bowel disease (IBD), is closely associated with CRC. Cheonggukjang (CJ), a traditional… read more here.
Keywords: colitis associated; effects cheonggukjang; colorectal cancer; associated colorectal ... See more keywords