Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys.
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.104859
Abstract: The outbreaks of Zika virus (ZIKV) infection in Brazil, 2015-2016, were associated with severe congenital malformations. Our translational study aimed to test the efficacy of the antiviral agent sofosbuvir (SOF) against vertical transmission of ZIKV… read more here.
Keywords: vertical transmission; congenital syndrome; zikv; associated congenital ... See more keywords
Incidence of biliary atresia associated congenital malformations: A retrospective multicenter study in China.
Sign Up to like & getrecommendations! Published in 2017 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2016.04.003
Abstract: BACKGROUND Some patients with biliary atresia (BA) have associated anomalies. Our study aimed to investigate the incidence of BA-associated malformations in mainland China, and compare the results with those reported in the Western literature. METHODS… read more here.
Keywords: biliary atresia; associated congenital; atresia associated; congenital malformations ... See more keywords
KLF1 E325K-associated Congenital Dyserythropoietic Anemia Type IV: Insights Into the Variable Clinical Severity
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001056
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: anemia type; klf1 e325k; e325k associated; associated congenital ... See more keywords
Microtia in a Chinese Specialty Clinic Population: Clinical Heterogeneity and Associated Congenital Anomalies
Sign Up to like & getrecommendations! Published in 2018 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000005066
Abstract: Background: Microtia is a congenital anomaly of the external ear that can appear in isolation or in association with other congenital anomalies. In this study, the authors identify the prevalence and phenotypes of associated congenital… read more here.
Keywords: microtia chinese; congenital anomalies; chinese specialty; associated congenital ... See more keywords
Sequence of Surgical Reconstruction in a Child With Cleft Lip and Palate Associated With Congenital Facial Teratomas.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000003536
Abstract: We describe a case of left homolateral complete cleft lip/palate associated with a congenital left maxillary teratoma and left orbital teratoma. The patient required step-by-step reconstruction that first included resection of the 2 teratomas in… read more here.
Keywords: reconstruction; lip palate; associated congenital; palate ... See more keywords
SCN10A variants associated with congenital harlequin syndrome
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Dermatology"
DOI: 10.1111/bjd.21011
Abstract: vs. 10%) and more frequent need for mechanical ventilation (48% vs. 5%). Besides older patients, with a poor outcome as expected, our study identified two distinct profiles of EN in younger patients. The first was… read more here.
Keywords: variants associated; syndrome; harlequin syndrome; scn10a variants ... See more keywords
Phosphodiesterase type 5 inhibitors improve microvascular dysfunction markers in pulmonary arterial hypertension associated with congenital heart disease
Sign Up to like & getrecommendations! Published in 2019 at "Congenital Heart Disease"
DOI: 10.1111/chd.12688
Abstract: BACKGROUND Ideally, vasodilator therapies for pulmonary arterial hypertension (PAH) should have a favorable impact on markers of vascular dysfunction, in addition to their known effects on hemodynamics, cardiac function, and patient's physical capacity. METHODS We… read more here.
Keywords: heart disease; dysfunction; congenital heart; associated congenital ... See more keywords
Melatonin protected against the detrimental effects of microRNA‐363 in a rat model of vitamin A‐associated congenital spinal deformities: Involvement of Notch signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12558
Abstract: Congenital spinal deformities are a result of defective somitogenesis and are associated with vitamin A deficiency (VAD). However, the molecular mechanisms of VAD‐associated congenital spinal deformities remain largely unknown. Increasing number of studies suggested that… read more here.
Keywords: spinal deformities; congenital spinal; mir 363; associated congenital ... See more keywords
P127 Pulmonary hypertension associated with congenital heart disease (clinical case)
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2017-313273.215
Abstract: Pulmonary Hypertension (PH) represents infrequent, but unresolved paediatric issue. It leads to progressive right ventricular insufficiency, considerably declines children’s quality of life and causes premature death. Most cases of paediatric PH are associated with congenital… read more here.
Keywords: clinical case; heart; pulmonary hypertension; heart disease ... See more keywords
Birth Defects Associated With Congenital Zika Virus Infection in Mexico
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Pediatrics"
DOI: 10.1177/0009922817738341
Abstract: Part of the work agenda of international health authorities is to define the clinical spectrum of the congenital Zika syndrome (CZS) in different territories. We describe the clinical variability that gave rise to the suspicion… read more here.
Keywords: birth defects; congenital zika; defects associated; infection ... See more keywords
Torsed extralobar pulmonary sequestration associated with congenital lobar emphysema: a rare entity
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/17534666231164535
Abstract: Pulmonary sequestration (PS) is a rare congenital malformation, which mainly contains two variants involving extralobar and intralobar sequestrations. Extralobar sequestrations (ELS) are isolated from the remaining lung tissue and have their visceral pleura. Herein, we… read more here.
Keywords: congenital lobar; lobar emphysema; lobar; pulmonary sequestration ... See more keywords