GW29-e1539 Dab2 gene variants are associated with coronary artery disease risk in the Chinese Han population
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.176
Abstract: Disabled-2 (Dab2) is a clathrin and cargo binding endocytic adaptor protein and cell biology studies revealed that Dab2 plays a role in cellular trafficking of a number of transmembrane receptors and signaling proteins. However, little… read more here.
Keywords: gw29 e1539; gene variants; dab2 gene; variants associated ... See more keywords
Anxiety is associated with coronary microvascular dysfunction: Results from the CAMADA study
Sign Up to like & getrecommendations! Published in 2023 at "Microcirculation"
DOI: 10.1111/micc.12798
Abstract: Coronary microvascular dysfunction (CMD) is an important component of ischemic heart disease. Here, we assessed the associations between anxiety/depression and CMD using coronary microvascular function indicators. read more here.
Keywords: anxiety associated; microvascular dysfunction; associated coronary; coronary microvascular ... See more keywords
New Insights into the Association between Fibrinogen and Coronary Atherosclerotic Plaque Vulnerability: An Intravascular Optical Coherence Tomography Study
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DOI: 10.1155/2019/8563717
Abstract: Background Fibrinogen levels have been associated with coronary plaque vulnerability in experimental studies. However, it has yet to be determined if serum fibrinogen levels are independently associated with coronary plaque vulnerability as detected by optical… read more here.
Keywords: optical coherence; fibrinogen; plaque vulnerability; vulnerability ... See more keywords
Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010680
Abstract: Genome-wide association studies have identified >250 genetic variants associated with coronary artery disease (CAD), but the causal variants, genes and molecular mechanisms remain unknown at most loci. We performed pooled CRISPR screens to test the… read more here.
Keywords: associated coronary; endothelial cells; crispr perturbations; artery disease ... See more keywords