TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109705
Abstract: Mouse embryonic stem cells (mESCs) can be maintained in vitro in defined N2B27 medium supplemented with two chemical inhibitors for GSK3 and MEK (2i) and the cytokine leukemia inhibitory factor (LIF), which act synergistically to promote… read more here.
Keywords: tcf lef; topologically associated; associated domain; exit pluripotent ... See more keywords
Elastic anomalies associated with domain switching in BaTiO3 single crystals under in situ electrical cycling
Sign Up to like & getrecommendations! Published in 2019 at "APL Materials"
DOI: 10.1063/1.5088749
Abstract: The elastic response of BaTiO$_3$ single crystals during electric field cycling at room temperature has been studied using in-situ Resonant Ultrasound Spectroscopy (RUS), which allows monitoring of both the elastic and anelastic changes caused by… read more here.
Keywords: anomalies associated; single crystals; domain switching; elastic anomalies ... See more keywords
Disruption of the topologically associated domain at Xp21.2 is related to 46, XY gonadal dysgenesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Genetics"
DOI: 10.1136/jmg-2022-108635
Abstract: Background Duplications at the Xp21.2 locus have previously been linked to 46,XY gonadal dysgenesis (GD), which is thought to result from gene dosage effects of NR0B1 (DAX1), but the exact disease mechanism remains unknown. Methods… read more here.
Keywords: disruption topologically; xp21; gonadal dysgenesis; associated domain ... See more keywords