Systematic In‐Depth Proteomic Analysis of Mitochondria‐Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700478
Abstract: Mitochondria‐associated endoplasmic reticulum membranes (MAMs) regulate important cellular functions including calcium signaling, bioenergetics, and apoptosis during neurodevelopment and carcinogenesis, but its function in male reproduction and spermatogenesis remains enigmatic because the field lacks a complete… read more here.
Keywords: endoplasmic reticulum; analysis; associated endoplasmic; mitochondria associated ... See more keywords
Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109134
Abstract: SUMMARY Axonal generation of Alzheimer’s disease (AD)-associated amyloid-β (Aβ) plays a key role in AD neuropathology, but the cellular mechanisms involved in its release have remained elusive. We previously reported that palmitoylated APP (palAPP) partitions… read more here.
Keywords: endoplasmic reticulum; axonal generation; associated endoplasmic; generation ... See more keywords
Mitochondria‐associated endoplasmic reticulum membrane: Overview and inextricable link with cancer
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17696
Abstract: The mitochondrial‐associated membrane (MAM) is a physical platform that facilitates communication between the endoplasmic reticulum (ER) and mitochondria. It is enriched with many proteins and enzymes and plays an important role in the regulation of… read more here.
Keywords: endoplasmic reticulum; membrane; cancer; associated endoplasmic ... See more keywords
Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum
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DOI: 10.1186/s12915-017-0361-y
Abstract: BackgroundMitochondria of opisthokonts undergo permanent fission and fusion throughout the cell cycle. Here, we investigated the dynamics of the mitosomes, the simplest forms of mitochondria, in the anaerobic protist parasite Giardia intestinalis, a member of… read more here.
Keywords: endoplasmic reticulum; giardia intestinalis; associated endoplasmic; fusion ... See more keywords
Mitochondria-associated endoplasmic reticulum membranes and cardiac hypertrophy: Molecular mechanisms and therapeutic targets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1015722
Abstract: Cardiac hypertrophy has been shown to compensate for cardiac performance and improve ventricular wall tension as well as oxygen consumption. This compensatory response results in several heart diseases, which include ischemia disease, hypertension, heart failure,… read more here.
Keywords: endoplasmic reticulum; hypertrophy; cardiac hypertrophy; associated endoplasmic ... See more keywords
The contribution of mitochondria-associated endoplasmic reticulum membranes (MAMs) dysfunction in Alzheimer’s disease and the potential countermeasure
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1158204
Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disease. There are many studies targeting extracellular deposits of amyloid β-peptide (Aβ) and intracellular neurofibrillary tangles (NFTs), however, there are no effective treatments to halt the progression.… read more here.
Keywords: endoplasmic reticulum; disease; alzheimer disease; reticulum membranes ... See more keywords