Two Birds with One Stone: Guanidyl Carbon Dots with Enhanced Antioxidative and Lipolytic Functions in Metabolic Associated Fatty Liver
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202406096
Abstract: Metabolic‐associated fatty liver disease (MAFLD) has become one of the most widespread metabolic diseases nowadays, while no definitive agent is approved for practical treatment. Given excessive lipid deposition and cellular oxidative stress are two main… read more here.
Keywords: two birds; carbon dots; birds one; associated fatty ... See more keywords
Hepatic‐Accumulated Obeticholic Acid and Atorvastatin Self‐Assembled Nanocrystals Potentiate Ameliorative Effects in Treatment of Metabolic‐Associated Fatty Liver Disease
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DOI: 10.1002/advs.202308866
Abstract: Exploration of medicines for efficient and safe management of metabolic‐associated fatty liver disease (MAFLD) remains a challenge. Obeticholic acid (OCA), a selective farnesoid X receptor agonist, has been reported to ameliorate injury and inflammation in… read more here.
Keywords: acid; associated fatty; metabolic associated; obeticholic acid ... See more keywords
Endoplasmic reticulum stress in nonalcoholic (metabolic associated) fatty liver disease (NAFLD/MAFLD)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30247
Abstract: Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation in the absence of excessive alcohol consumption and is strongly associated with obesity, type 2 diabetes (T2DM) and other metabolic syndrome features. NAFLD is… read more here.
Keywords: disease nafld; fatty liver; mafld; liver disease ... See more keywords
Endurance Training Alleviates Metabolic‐Associated Fatty‐Liver Disease (MAFLD)‐Related Testicular Impairments via Endoplasmic Reticulum Stress Regulation
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.70042
Abstract: Metabolic‐associated fatty liver disease (MAFLD), the most prevalent liver disorder globally, affects 20%–40% of the population and presents significant health challenges. Studies link MAFLD to male reproductive dysfunction, highlighting the need for effective interventions. This… read more here.
Keywords: associated fatty; disease mafld; endurance training; metabolic associated ... See more keywords
ACSL1 Contributes to Metabolic-Associated Fatty Liver Disease by Mediating Arachidonic Acid Metabolism.
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DOI: 10.1002/lipd.70016
Abstract: The precise involvement of ACSL1 in metabolic-associated fatty liver disease (MAFLD) pathogenesis remains unclear. To this end, we analyzed the effects of long-chain acyl-CoA synthase (ACSL1) on MAFLD. Analysis of GEO datasets showed that ACSL1… read more here.
Keywords: acsl1; acid; mafld; associated fatty ... See more keywords
In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2024 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-024-10219-1
Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a major health risk and a serious worldwide issue. MAFLD typically arises from aberrant lipid metabolism, insulin resistance, oxidative stress, and inflammation. However, subjacent causes are multifactorial.… read more here.
Keywords: disease; dysfunction associated; associated fatty; metabolic dysfunction ... See more keywords
Cholecystectomy as a risk factor for metabolic dysfunction-associated fatty liver disease: unveiling the metabolic and chronobiologic clues behind the bile acid enterohepatic circulation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of physiology and biochemistry"
DOI: 10.1007/s13105-020-00782-w
Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) is highly prevalent worldwide. Recent clinical and experimental studies have addressed the association between cholecystectomy and MAFLD, confirming that cholecystectomy is an independent risk factor for MAFLD. In this… read more here.
Keywords: fatty liver; liver disease; associated fatty; dysfunction associated ... See more keywords
Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice
Sign Up to like & getrecommendations! Published in 2022 at "Redox Biology"
DOI: 10.1016/j.redox.2022.102277
Abstract: Glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase that facilitates glutathionylation/de-glutathionylation of target proteins. The main variants of Grx2 are the mitochondrial Grx2a and the cytosolic Grx2c. The aim of this study was to investigate the… read more here.
Keywords: metabolic dysfunction; associated fatty; liver disease; fatty liver ... See more keywords
Hydroxytyrosol Improves Metabolic Dysfunction-Associated Fatty Liver Disease Dependent on the Modulation of Gut Microbiota.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c07003
Abstract: The global threat of metabolic dysfunction-associated fatty liver disease (MAFLD) is significant, but effective measures are still lacking. To explore the potential impact of hydroxytyrosol (HT), a plant polyphenol, in the metabolic outcomes of MAFLD… read more here.
Keywords: gut microbiota; dysfunction associated; associated fatty; metabolic dysfunction ... See more keywords
Association between TyG related parameters and metabolic dysfunction associated fatty liver disease among nondiabetic individuals
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-024-84917-9
Abstract: Metabolic dysfunction associated fatty liver disease (MAFLD) is a prevalent liver condition and presents a major clinical and public health problem worldwide. TyG index and its related parameters TyG-WHtR, TyG-WC and TyG-BMI have been proven… read more here.
Keywords: tyg; dysfunction associated; associated fatty; related parameters ... See more keywords
Pistacia atlantica can improve oxidative status in patients with metabolic dysfunction-associated fatty liver disease
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-04107-z
Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a problem worldwide. Oxidative stress is important factor in beginning and progress of MAFLD. This study is the first clinical trial with the aim of determining the effect… read more here.
Keywords: dysfunction associated; group; associated fatty; metabolic dysfunction ... See more keywords