Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine.
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DOI: 10.1016/j.lfs.2021.119274
Abstract: BACKGROUND The use of immunosuppressive and antifibrotic agents for the treatment of chronic hypersensitivity pneumonitis (CHP) appears promising, but there is still no evidence supporting the clinical decision regarding the implementation of each specific pharmacological… read more here.
Keywords: associated favourable; response; treatment; chronic hypersensitivity ... See more keywords
Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles
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DOI: 10.1038/s41416-021-01310-3
Abstract: Background Immune checkpoint blockers (ICBs) activate CD8+ T cells, eliciting both anti-cancer activity and immune-related adverse events (irAEs). The relationship of irAEs with baseline parameters and clinical outcome is unclear. Methods Retrospective evaluation of irAEs… read more here.
Keywords: associated favourable; outcome; metastatic melanoma; expression ... See more keywords
Cytoplasmic location of NR4A1 in aggressive lymphomas is associated with a favourable cancer specific survival
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DOI: 10.1038/s41598-018-32972-4
Abstract: The nuclear orphan receptor NR4A1 functions as tumour suppressor in aggressive lymphomas by pro-apoptotic genomic and non-genomic effects. Here, we immunohistochemically studied the clinico-pathological relevance of NR4A1 protein expression patterns in a cohort of 60… read more here.
Keywords: associated favourable; cytoplasmic nr4a1; aggressive lymphomas; favourable cancer ... See more keywords