Articles with "associated gene" as a keyword



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A cohesin‐associated gene score may predict immune checkpoint blockade in hepatocellular carcinoma

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13474

Abstract: Stromal antigen 1 (STAG1), a component of cohesion, is overexpressed in various cancers, but it is unclear whether it has a role in the transcriptional regulation of hepatocellular carcinoma (HCC). To test this hypothesis, here,… read more here.

Keywords: hepatocellular carcinoma; associated gene; cohesin associated; gene score ... See more keywords
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Melanoma Differentiation Associated Gene-9/Syndecan Binding Protein (MDA-9/SDCBP) Promotes Hepatocellular Carcinoma (HCC).

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Published in 2022 at "Hepatology"

DOI: 10.1002/hep.32797

Abstract: The oncogene Melanoma differentiation associated gene-9/syndecan binding protein (MDA-9/SDCBP) is overexpressed in many cancers promoting aggressive, metastatic disease. However, the role of MDA-9 in regulating hepatocellular carcinoma (HCC) has not been well-studied. To unravel the… read more here.

Keywords: alb mda; mda; associated gene; hcc ... See more keywords

A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma.

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Published in 2022 at "Computers in biology and medicine"

DOI: 10.1016/j.compbiomed.2022.105394

Abstract: BACKGROUND The mechanistic target of rapamycin (mTOR) was proven to have great impact on apoptosis, cell proliferation, autophagy, and many other fundamental cellular processes; moreover, it closely correlates with tumor occurrence and development. However, few… read more here.

Keywords: analysis; associated gene; signature; mtor associated ... See more keywords
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The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-07573-2

Abstract: Myocardial infarction (MI) is an ischaemic heart condition caused by the occlusion of coronary arteries. Following MI, lactic acid from anaerobic glycolysis increases and infiltrating immune cells produce severe inflammation, which leads to acidosis in… read more here.

Keywords: tdag8; associated gene; myocardial infarction; cell death ... See more keywords
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Transgenic manipulation of triacylglycerol biosynthetic enzymes in B. napus alters lipid-associated gene expression and lipid metabolism

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Published in 2022 at "Scientific Reports"

DOI: 10.1038/s41598-022-07387-x

Abstract: Oilseed rape ( Brassica napus ) is an important crop that is cultivated for the oil (mainly triacylglycerol; TAG) it produces in its seeds. TAG synthesis is controlled mainly by key enzymes in the Kennedy… read more here.

Keywords: expression; lipid metabolism; associated gene; gene expression ... See more keywords
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Lipid Composition and Associated Gene Expression Patterns during Pollen Germination and Pollen Tube Growth in Olive (Olea europaea L.)

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Published in 2020 at "Plant and Cell Physiology"

DOI: 10.1093/pcp/pcaa063

Abstract: Abstract Pollen lipids are essential for sexual reproduction, but our current knowledge regarding lipid dynamics in growing pollen tubes is still very scarce. Here, we report unique lipid composition and associated gene expression patterns during… read more here.

Keywords: associated gene; composition associated; pollen germination; pollen ... See more keywords
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OmpA protein sequence-based typing and virulence-associated gene profiles of Pasteurella multocida isolates associated with bovine haemorrhagic septicaemia and porcine pneumonic pasteurellosis in Thailand

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Published in 2017 at "BMC Veterinary Research"

DOI: 10.1186/s12917-017-1157-6

Abstract: BackgroundPasteurella multocida is a Gram-negative bacterium that causes economically significant infections of a broad range of animal species. Pneumonic and septicaemic pasteurellosis caused by this bacterium remain important problems in pigs, cattle, and water buffaloes… read more here.

Keywords: virulence associated; gene profiles; associated gene; porcine ... See more keywords
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Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis.

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Published in 2023 at "Aging"

DOI: 10.18632/aging.204737

Abstract: Environmental and physiological stresses can accelerate Alzheimer's disease (AD) pathogenesis. Under stress, a cytoplasmic membraneless structure termed a stress granule (SG) is formed and is associated with various neurodegenerative disorders, including AD. SGs contain translationally… read more here.

Keywords: stress; associated gene; disease; alzheimer disease ... See more keywords
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Integrative analyses of prognosis, tumor immunity, and ceRNA network of the ferroptosis-associated gene FANCD2 in hepatocellular carcinoma

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.955225

Abstract: Extensive evidence has revealed that ferroptosis plays a vital role in HCC development and progression. Fanconi anemia complementation group D2 (FANCD2) has been reported to serve as a ferroptosis-associated gene and has a close relationship… read more here.

Keywords: associated gene; hcc; fancd2; ferroptosis associated ... See more keywords
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Rare complications of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis: Time to nip them in the bud

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1009546

Abstract: Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+ DM) is an infrequent autoimmune disease, which mainly distributes in Asians and females. MDA5+ DM usually presents various skin lesions and positive anti-MDA5 antibody (a myositis-specific autoantibody for… read more here.

Keywords: rare complications; associated gene; differentiation associated; melanoma differentiation ... See more keywords
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Pathogenesis of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis: A Concise Review With an Emphasis on Type I Interferon System

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Published in 2021 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2021.833114

Abstract: Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+ DM) is typically characterized by cutaneous manifestations, amyopathic or hypomyopathic muscle involvement, and a high incidence of rapid progressive interstitial lung disease (RP-ILD). However, the exact etiology and… read more here.

Keywords: melanoma differentiation; associated gene; differentiation associated; gene ... See more keywords