Mutations in gliclazide‐associated genes may predict poor bladder cancer prognosis
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12583
Abstract: In recent years, an increasing number of patients have had diabetes and cancer simultaneously; thus, it is crucial for physicians to select hypoglycemic drugs with the lowest risk of inducing cancer. Gliclazide is a widely… read more here.
Keywords: bladder cancer; analysis; cancer; predict poor ... See more keywords
Transcriptomic analysis of diapause-associated genes in Exorista civilis Rondani (Diptera:Tachinidae).
Sign Up to like & getrecommendations! Published in 2021 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21789
Abstract: Exorista civilis Rondani (Diptera:Tachinidae) is an excellent dominant parasitic enemy all over the world. But there has been a lack of research on the molecular regulation of diapause in E. civilis. To investigate the important… read more here.
Keywords: exorista civilis; civilis rondani; rondani diptera; diapause associated ... See more keywords
SET domain‐containing protein 5 is required for expression of primordial germ cell specification‐associated genes in murine embryonic stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3269
Abstract: Primordial germ cell (PGC) specification is one of the most fundamental processes in developmental biology. Because PGCs are a common source of both gametes, generation of PGCs from embryonic stem cells (ESCs) is a useful… read more here.
Keywords: protein; primordial germ; associated genes; germ cell ... See more keywords
NGS testing for cardiomyopathy: Utility of adding RASopathy‐associated genes
Sign Up to like & getrecommendations! Published in 2018 at "Human Mutation"
DOI: 10.1002/humu.23535
Abstract: RASopathies include a group of syndromes caused by pathogenic germline variants in RAS‐MAPK pathway genes and typically present with facial dysmorphology, cardiovascular disease, and musculoskeletal anomalies. Recently, variants in RASopathy‐associated genes have been reported in… read more here.
Keywords: utility; ngs testing; rasopathy associated; adding rasopathy ... See more keywords
Burden of rare variants in arrhythmogenic cardiomyopathy with right dominant form‐associated genes provides new insights for molecular diagnosis and clinical management
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24436
Abstract: Arrhythmogenic cardiomyopathy with right dominant form (ACR) is a rare heritable cardiac cardiomyopathy disorder associated with sudden cardiac death. Pathogenic variants (PVs) in desmosomal genes have been causally related to ACR in 40% of cases.… read more here.
Keywords: dominant form; diagnosis; arrhythmogenic cardiomyopathy; associated genes ... See more keywords
Computational Screening and Exploration of Disease‐Associated Genes in Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25806
Abstract: Alzheimer's is a neurodegenerative disease affecting large populations worldwide characterized mainly by progressive loss of memory along with various other symptoms. The foremost cause of the disease is still unclear, however various mechanisms have been… read more here.
Keywords: screening exploration; disease; computational screening; disease associated ... See more keywords
Identification of several senescence‐associated genes signature in head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24555
Abstract: As one of the core aging processes, cellular senescence is associated with tumorigenesis, growth, and immune modulation in cancers. Nevertheless, the prognosis of senescence‐associated genes (SAGs) signature in head and neck squamous cell carcinoma (HNSCC)… read more here.
Keywords: head neck; associated genes; senescence; signature head ... See more keywords
Imputed expression of schizophrenia‐associated genes and cognitive measures in patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1942
Abstract: Cognitive dysfunction is a core manifestation of schizophrenia and one of the best predictors of long‐term disability. Genes increasing risk for schizophrenia may partly act through the modulation of cognition. read more here.
Keywords: genes cognitive; associated genes; imputed expression; schizophrenia associated ... See more keywords
Identification and Functional Analysis of Senescence-Associated Genes in Wheat.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7672-0_19
Abstract: Senescence is the final stage of leaf development. During this process, different macromolecules undergo degradation, and the resulting components are transported to developing and storage tissues of the plant. Senescence-associated genes (SAGs) play important roles… read more here.
Keywords: associated genes; senescence associated; analysis; senescence ... See more keywords
The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.06.013
Abstract: Zebrafish is broadly used as a model organism in gene loss-of-function studies in vivo, but its employment in vitro is greatly limited by the lack of efficient gene knockdown approaches in zebrafish cell lines such… read more here.
Keywords: methodology; telomere associated; gene; zebrafish cell ... See more keywords
Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival
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DOI: 10.1016/j.ebiom.2019.01.041
Abstract: Background The incidence of narcolepsy rose sharply after the swine influenza A (H1N1) vaccination campaign with Pandemrix. Narcolepsy is an immune-related disorder with excessive daytime sleepiness. The most frequent form is strongly associated with HLA-DQB1*06:02,… read more here.
Keywords: pandemrix induced; gdnf; narcolepsy associated; induced narcolepsy ... See more keywords