Long-term Benefits and Harms Associated With Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.3728
Abstract: Importance The balance between the potential long-term clinical benefits and harms associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking pharmacologic CETP inhibition, is unknown. Objective To assess the relative benefits and harms associated… read more here.
Keywords: hdl cholesterol; risk; associated genetic; cholesterol ... See more keywords
Neglected impacts of patient decision-making associated with genetic testing
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462322000575
Abstract: Abstract We highlight non-health-related impacts associated with genetic testing (GT) and knowing one’s genetic status so that health technology assessment (HTA) analysts and HTA audiences may more appropriately consider the pros and cons of GT.… read more here.
Keywords: health; associated genetic; non health; genetic testing ... See more keywords
Genomic evidence for contrasting patterns of host‐associated genetic differentiation across shared host‐plant species in leaf‐ and bud‐galling sawflies
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Ecology"
DOI: 10.1111/mec.16844
Abstract: Resource specialization and ecological speciation arising through host‐associated genetic differentiation (HAD) are frequently invoked as an explanation for the high diversity of plant‐feeding insects and other organisms with a parasitic lifestyle. While genetic studies have… read more here.
Keywords: associated genetic; host associated; genetic differentiation; patterns host ... See more keywords
Glucose-6-phosphate dehydrogenase activity measured by spectrophotometry and associated genetic variants from the Oromiya zone, Ethiopia
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DOI: 10.1186/s12936-018-2510-3
Abstract: BackgroundThe study aimed to gain first data on the prevalence of G6PD enzyme deficiency measured by spectrophotometry and associated genetic variants in Jimma and surroundings, Ethiopia. The area is a Plasmodium vivax endemic region, but… read more here.
Keywords: g6pd; measured spectrophotometry; associated genetic; spectrophotometry ... See more keywords
Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses
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DOI: 10.1371/journal.pgen.1009762
Abstract: The development of genome-informed methods for identifying quantitative trait loci (QTL) and studying the genetic basis of quantitative variation in natural and experimental populations has been driven by advances in high-throughput genotyping. For many complex… read more here.
Keywords: trait; marker associated; large effect; associated genetic ... See more keywords