Postbiotics From Lactobacillus Johnsonii Activates Gut Innate Immunity to Mitigate Alcohol‐Associated Liver Disease
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DOI: 10.1002/advs.202405781
Abstract: Prolonged alcohol consumption disrupts the gut microbiota and the immune system, contributing to the pathogenesis of alcohol‐associated liver disease (ALD). Probiotic‐postbiotic intervention strategies can effectively relieve ALD by maintaining gut homeostasis. Herein, the efficacy of… read more here.
Keywords: lactobacillus johnsonii; associated liver; alcohol associated; johnsonii ... See more keywords
New Insights Into Intestinal Failure–Associated Liver Disease in Children
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DOI: 10.1002/hep.31152
Abstract: Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components… read more here.
Keywords: failure associated; associated liver; intestinal failure; new insights ... See more keywords
Reducing the Global Burden of Alcohol‐Associated Liver Disease: A Blueprint for Action
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DOI: 10.1002/hep.31583
Abstract: Alcohol‐associated liver disease (ALD) is a major driver of global liver related morbidity and mortality. There are 2.4 billion drinkers (950 million heavy drinkers) and the lifetime prevalence of any alcohol use disorder (AUD) is… read more here.
Keywords: alcohol associated; associated liver; global burden; liver disease ... See more keywords
Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease
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DOI: 10.1007/s00535-024-02168-x
Abstract: Fontan-associated liver disease (FALD) is a type of progressive liver fibrosis that occurs following Fontan surgery and can be complicated by hepatocellular carcinoma (HCC). Established treatments for FALD are lacking. Therefore, we investigated the efficacy… read more here.
Keywords: ursodeoxycholic acid; treatment; associated liver; hcc ... See more keywords
Intestinal failure-associated liver disease (IFALD): insights into pathogenesis and advances in management
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DOI: 10.1007/s12072-020-10048-8
Abstract: Premature infants and children with intestinal failure (IF) or short bowel syndrome are susceptible to intestinal failure-associated liver disease (IFALD, previously referred to as parenteral nutrition-associated liver disease, or PNALD). IFALD in children is characterized… read more here.
Keywords: associated liver; liver disease; failure associated; intestinal failure ... See more keywords
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake
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DOI: 10.1016/j.ebiom.2018.08.006
Abstract: Although the pathogenesis of intestinal failure (IF)-associated liver disease (IFALD) is uncertain, IF-associated cholestasis mediated by the combination of intestinal injury and parenteral nutrition (PN) can lead to disturbed hepatocyte bile acids (BA) homeostasis and… read more here.
Keywords: failure associated; bile acids; disease; associated liver ... See more keywords
Fontan-associated Liver Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2017.10.052
Abstract: Fontan-associated liver disease refers to the disturbance in the liver secondary to hemodynamic changes and systemic venous congestion following Fontan surgery. Although the natural history of this disease has not yet been established, patients with… read more here.
Keywords: associated liver; liver disease; fontan associated;
Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy
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DOI: 10.1016/j.toxrep.2021.02.010
Abstract: Highlights • Chronic intake of alcohol initiates a pathogenic process that involves the production of protein-aldehyde adducts, and release of cytokines.• Involved gene polymorphisms may include alcohol dehydrogenase, cytochrome P4502E1, and those associated with alcoholism.•… read more here.
Keywords: alcohol associated; associated liver; disease review; review pathophysiology ... See more keywords
FONTAN-ASSOCIATED LIVER DISEASE: IS INSULIN SENSITIVITY IMPORTANT?
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DOI: 10.1016/s0735-1097(20)31176-1
Abstract: Adults with a Fontan palliation are known to have Fontan-associated liver disease (FALD). Traditional markers of liver dysfunction, however, have not correlated with the degree of FALD. Based upon the role of the liver in… read more here.
Keywords: associated liver; liver disease; fontan associated; insulin sensitivity ... See more keywords
Minibioreactor arrays to model microbiome response to alcohol and tryptophan in the context of alcohol-associated liver disease
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DOI: 10.1038/s41522-024-00602-9
Abstract: The intestinal microbiota (IM) plays a role in the severity of alcohol-associated liver disease. Modifying severe alcohol-associated hepatitis (AH) dysbiosis improves liver injury through tryptophan (Trp) metabolites and the aryl hydrocarbon receptor (AhR). However, Trp’s… read more here.
Keywords: minibioreactor arrays; associated liver; alcohol associated; trp ... See more keywords
MIR17HG polymorphism (rs7318578) is associated with liver cancer risk in the Chinese Han population
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DOI: 10.1042/bsr20193312
Abstract: Abstract Numerous evidence has revealed that single-nucleotide polymorphisms (SNPs) are associated with liver cancer risk. To assess whether the MIR17HG polymorphisms are associated with the liver cancer risk in the Chinese Han population, we performed… read more here.
Keywords: associated liver; cancer; cancer risk; liver cancer ... See more keywords