New Insights Into Intestinal Failure–Associated Liver Disease in Children
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DOI: 10.1002/hep.31152
Abstract: Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components… read more here.
Keywords: failure associated; associated liver; intestinal failure; new insights ... See more keywords
Reducing the Global Burden of Alcohol‐Associated Liver Disease: A Blueprint for Action
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DOI: 10.1002/hep.31583
Abstract: Alcohol‐associated liver disease (ALD) is a major driver of global liver related morbidity and mortality. There are 2.4 billion drinkers (950 million heavy drinkers) and the lifetime prevalence of any alcohol use disorder (AUD) is… read more here.
Keywords: alcohol associated; associated liver; global burden; liver disease ... See more keywords
Intestinal failure-associated liver disease (IFALD): insights into pathogenesis and advances in management
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology International"
DOI: 10.1007/s12072-020-10048-8
Abstract: Premature infants and children with intestinal failure (IF) or short bowel syndrome are susceptible to intestinal failure-associated liver disease (IFALD, previously referred to as parenteral nutrition-associated liver disease, or PNALD). IFALD in children is characterized… read more here.
Keywords: associated liver; liver disease; failure associated; intestinal failure ... See more keywords
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.08.006
Abstract: Although the pathogenesis of intestinal failure (IF)-associated liver disease (IFALD) is uncertain, IF-associated cholestasis mediated by the combination of intestinal injury and parenteral nutrition (PN) can lead to disturbed hepatocyte bile acids (BA) homeostasis and… read more here.
Keywords: failure associated; bile acids; disease; associated liver ... See more keywords
Fontan-associated Liver Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2017.10.052
Abstract: Fontan-associated liver disease refers to the disturbance in the liver secondary to hemodynamic changes and systemic venous congestion following Fontan surgery. Although the natural history of this disease has not yet been established, patients with… read more here.
Keywords: associated liver; liver disease; fontan associated;
Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology Reports"
DOI: 10.1016/j.toxrep.2021.02.010
Abstract: Highlights • Chronic intake of alcohol initiates a pathogenic process that involves the production of protein-aldehyde adducts, and release of cytokines.• Involved gene polymorphisms may include alcohol dehydrogenase, cytochrome P4502E1, and those associated with alcoholism.•… read more here.
Keywords: alcohol associated; associated liver; disease review; review pathophysiology ... See more keywords
FONTAN-ASSOCIATED LIVER DISEASE: IS INSULIN SENSITIVITY IMPORTANT?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)31176-1
Abstract: Adults with a Fontan palliation are known to have Fontan-associated liver disease (FALD). Traditional markers of liver dysfunction, however, have not correlated with the degree of FALD. Based upon the role of the liver in… read more here.
Keywords: associated liver; liver disease; fontan associated; insulin sensitivity ... See more keywords
MIR17HG polymorphism (rs7318578) is associated with liver cancer risk in the Chinese Han population
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193312
Abstract: Abstract Numerous evidence has revealed that single-nucleotide polymorphisms (SNPs) are associated with liver cancer risk. To assess whether the MIR17HG polymorphisms are associated with the liver cancer risk in the Chinese Han population, we performed… read more here.
Keywords: associated liver; cancer; cancer risk; liver cancer ... See more keywords
Pregnancy-Associated Liver Diseases.
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DOI: 10.1053/j.gastro.2022.01.060
Abstract: The liver disorders unique to pregnancy include hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy and pre-eclampsia-associated hepatic impairment, specifically hemolysis, elevated liver enzymes, and low platelet count syndrome (HELLP). Their importance… read more here.
Keywords: liver; medicine; associated liver; pregnancy ... See more keywords
NATURAL HISTORY OF ALCOHOL-ASSOCIATED LIVER DISEASE: UNDERSTANDING THE CHANGING LANDSCAPE OF PATHOPHYSIOLOGY AND PATIENT CARE.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.05.031
Abstract: Alcohol and consequent liver disease are a major burden, which has worsened during the COVID-19 pandemic. There are several facets to the pathophysiology and clinical consequences of alcohol-use disorder (AUD) and progression to alcohol-associated liver… read more here.
Keywords: natural history; associated liver; alcohol associated; history alcohol ... See more keywords
Inflammation in alcohol-associated liver disease progression.
Sign Up to like & getrecommendations! Published in 2022 at "Zeitschrift fur Gastroenterologie"
DOI: 10.1055/a-1714-9246
Abstract: Chronic alcohol consumption induces stress and damage in alcohol metabolising hepatocytes, which leads to inflammatory and fibrogenic responses. Besides these direct effects, alcohol disrupts intestinal barrier functions and induces gut microbial dysbiosis, causing translocation of… read more here.
Keywords: alcohol associated; liver disease; alcohol; associated liver ... See more keywords