Regulation of Mitochondrial Dynamics and Autophagy by the Mitochondria-Associated Membrane.
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DOI: 10.1007/978-981-10-4567-7_3
Abstract: Mitochondria are powerhouses and central to metabolism in cells. They are highly dynamic organelles that continuously fuse, divide, and move along the cytoskeleton to form the mitochondrial network. The fusion and fission are catalyzed by… read more here.
Keywords: regulation mitochondrial; endoplasmic reticulum; mitochondria associated; associated membrane ... See more keywords
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins
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DOI: 10.1186/s13062-021-00311-9
Abstract: Background Rab32 is a small GTPase associated with multiple organelles but is particularly enriched at the endoplasmic reticulum (ER). Here, it controls targeting to mitochondria-ER contacts (MERCs), thus influencing composition of the mitochondria-associated membrane (MAM).… read more here.
Keywords: degradation; rab32; mitochondria associated; associated membrane ... See more keywords
MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy
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DOI: 10.3389/fmed.2021.670188
Abstract: Objective: Several clinical trials have suggested that autophagy inhibition is a promising approach for cancer therapy. However, the implications of autophagy in ameloblastoma (AB) remain undiscovered. This study investigated the dysregulated autophagy and its regulatory… read more here.
Keywords: protein; mediated autophagy; lysosomal associated; associated membrane ... See more keywords
Mitochondria-Associated Membrane Scaffolding with Endoplasmic Reticulum: A Dynamic Pathway of Developmental Disease
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DOI: 10.3389/fmolb.2022.908721
Abstract: Communication between intracellular organelles is essential for overall cellular function. How this communication occurs and under what circumstances alterations transpire are only the beginning to be elucidated. The pathways of calcium homeostasis, lipid transfer, mitochondrial… read more here.
Keywords: membrane scaffolding; endoplasmic reticulum; associated membrane; reticulum ... See more keywords
Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer
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DOI: 10.7150/jca.25666
Abstract: Translocation associated membrane protein 2 (TRAM2) has been characterized as a component of the translocon that is a gated channel at the endoplasmic reticulum (ER) membrane. TRAM2 is expressed in a wide variety of human… read more here.
Keywords: protein; associated membrane; cancer; membrane protein ... See more keywords