Longitudinal monitoring reveals dynamic changes in circulating tumor cells (CTCs) and CTC-associated miRNAs in response to chemotherapy in metastatic colorectal cancer patients.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.02.039
Abstract: We evaluated the changes in CTC count and CTC-associated miRNAs during the course of chemotherapy in patients with metastatic colorectal cancer. Blood samples were collected from 9 metastatic colorectal cancer patients prior to chemotherapy and… read more here.
Keywords: metastatic colorectal; associated mirnas; colorectal cancer; ctc ... See more keywords
Target-mimicry based diminution of miRNA167 reinforced flowering-time phenotypes in tobacco via spatial-transcriptional biases of flowering-associated miRNAs.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.10.008
Abstract: Evolutionarily conserved microRNAs such as miR156, miR159, miR167 and miR172 tightly regulate the extensive array of gene expression during flowering in plants, through instant and long-term alterations in the expression of their target genes. Here… read more here.
Keywords: transcriptional biases; associated mirnas; biases flowering; target ... See more keywords
ASCL1 regulates super‐enhancer‐associated miRNAs to define molecular subtypes of small cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15481
Abstract: Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor with dismal prognosis. Recently, molecular subtypes of SCLC have been defined by the expression status of ASCL1, NEUROD1, YAP1, and POU2F3 transcription regulators. ASCL1… read more here.
Keywords: molecular subtypes; associated mirnas; small cell; ascl1 ... See more keywords
Discovery of inflammatory bowel disease-associated miRNAs using a novel bipartite clustering approach
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Genomics"
DOI: 10.1186/s12920-020-0660-y
Abstract: Multidimensional data mining from an integrated environment of different data sources is frequently performed in computational system biology. The molecular mechanism from the analysis of a complex network of gene-miRNA can aid to diagnosis and… read more here.
Keywords: bowel disease; associated mirnas; inflammatory bowel; analysis ... See more keywords
Extracellular Vesicles and Their Associated miRNAs as Potential Biomarkers in Intracranial Aneurysm
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.785314
Abstract: Intracranial aneurysms (IA) are abnormal expansions of the intracranial arteries. Once it ruptures, the mortality and disability rate are high. The cost of imaging examinations is high, and rupture risk cannot be predicted, making it… read more here.
Keywords: vesicles associated; extracellular vesicles; biomarkers intracranial; associated mirnas ... See more keywords
Senescence-Associated miRNAs and Their Role in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pathology and Oncology Research"
DOI: 10.3389/pore.2022.1610156
Abstract: Replicative senescence is irreversible cell proliferation arrest for somatic cells which can be circumvented in cancers. Cellular senescence is a process, which may play two opposite roles. On the one hand, this is a natural… read more here.
Keywords: pancreatic cancer; role; associated mirnas; senescence ... See more keywords
“Silicon-On-Insulator”-Based Nanosensor for the Revelation of MicroRNA Markers of Autism
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13020199
Abstract: MicroRNAs (miRNAs), which represent short (20 to 22 nt) non-coding RNAs, were found to play a direct role in the development of autism in children. Herein, a highly sensitive “silicon-on-insulator”-based nanosensor (SOI-NS) has been developed… read more here.
Keywords: revelation; based nanosensor; associated mirnas; insulator based ... See more keywords