Curcumin: An effective adjunct in patients with statin‐associated muscle symptoms?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12140
Abstract: In spite of the unequivocal efficacy of statins in reducing primary and secondary cardiovascular events, the use of these drugs in a considerable number of patients is limited because of statin intolerance, mainly statin‐associated muscle… read more here.
Keywords: curcumin effective; muscle; statin associated; associated muscle ... See more keywords
Low vitamin D does not predict statin associated muscle symptoms but is associated with transient increases in muscle damage and pain.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2016.11.011
Abstract: BACKGROUND AND AIMS Low vitamin D (VITD) may contribute to statin-associated muscle symptoms (SAMS). We examined the influence of baseline and change in VITD in patients with verified SAMS. METHODS SAMS was verified in 120… read more here.
Keywords: muscle; statin associated; vitd; associated muscle ... See more keywords
Serum uric acid is positively associated with muscle strength in older men and women: Findings from NHANES 1999-2002.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2020.12.043
Abstract: BACKGROUND One of the causes of strength loss in older adults is the increased oxidative stress; thus, substances with antioxidants properties may have protective effects on muscle strength. Uric acid (UA) is an important antioxidant… read more here.
Keywords: strength; muscle strength; strength older; associated muscle ... See more keywords
Statin-associated muscle symptoms-Managing the highly intolerant.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.01.006
Abstract: Musculoskeletal symptoms are the most commonly reported adverse effects associated with statin therapy. Yet, certain data indicate that these symptoms often present in populations with underlying musculoskeletal complaints and are not likely statin related. Switching… read more here.
Keywords: muscle; statin associated; associated muscle; highly intolerant ... See more keywords
Statin-associated muscle symptoms: beware of the nocebo effect
Sign Up to like & getrecommendations! Published in 2017 at "The Lancet"
DOI: 10.1016/s0140-6736(17)31163-7
Abstract: Full Text Tables and Figures References Patient-reported statin intolerance, predominantly due to statin-associated muscle symptoms (SAMS), is a common and difficult-to-manage condition affecting millions of patients worldwide. Different expert panels have proposed various definitions and… read more here.
Keywords: statin intolerance; statin associated; associated muscle; statin ... See more keywords
Effects of Vitamin D Supplementation in Patients with Statin-Associated Muscle Symptoms and Low Vitamin D Levels.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2021.0127
Abstract: Background: Statin therapy is a cornerstone of cardiovascular disease treatment and prevention. Unfortunately, 7%-29% of statin-treated patients complain of muscular fatigue, cramps, and/or pain (statin-associated muscle symptoms [SAMS]). In recent years, the important role of… read more here.
Keywords: vitamin levels; statin associated; associated muscle; muscle ... See more keywords
Coenzyme Q10 as Treatment for Statin-Associated Muscle Symptoms-A Good Idea, but….
Sign Up to like & getrecommendations! Published in 2018 at "Advances in nutrition"
DOI: 10.1093/advances/nmy010
Abstract: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are extremely well tolerated but are associated with a range of mild-to-moderate statin-associated muscle symptoms (SAMS). Estimates of SAMS incidence vary from read more here.
Keywords: statin associated; treatment; associated muscle; coenzyme ... See more keywords
Pharmacogenomic Study of Statin-Associated Muscle Symptoms in the ODYSSEY OUTCOMES Trial
Sign Up to like & getrecommendations! Published in 2022 at "Circulation. Genomic and Precision Medicine"
DOI: 10.1161/circgen.121.003503
Abstract: Background: Statin-associated muscle symptoms (SAMS) are the most frequently reported adverse events for statin therapies. Previous studies have reported an association between the p.Val174Ala missense variant in SLCO1B1 and SAMS in simvastatin-treated subjects; however, evidence… read more here.
Keywords: statin associated; odyssey outcomes; associated muscle; association ... See more keywords
Epigenetics of cancer-associated muscle catabolism.
Sign Up to like & getrecommendations! Published in 2017 at "Epigenomics"
DOI: 10.2217/epi-2017-0058
Abstract: Cancer patients are commonly affected by cachexia, a wasting process involving muscle and fat. Specifically, loss of the muscle compartment has been associated with poor prognosis and suboptimal response to therapy. Nutritional support has been… read more here.
Keywords: muscle; associated muscle; muscle catabolism; cancer ... See more keywords
Coenzyme Q10 supplementation for the treatment of statin-associated muscle symptoms.
Sign Up to like & getrecommendations! Published in 2022 at "Future cardiology"
DOI: 10.2217/fca-2021-0106
Abstract: Aim: To determine the association of coenzyme Q10 (CoQ10) use with the resolution of statin-associated muscle symptoms (SAMS). Patients & methods: Retrospective analysis of a large, multi-center survey study of SAMS (total n = 511; n = 64 CoQ10… read more here.
Keywords: coq10; statin associated; associated muscle; coenzyme q10 ... See more keywords
Sepsis-Associated Muscle Wasting: A Comprehensive Review from Bench to Bedside
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24055040
Abstract: Sepsis-associated muscle wasting (SAMW) is characterized by decreased muscle mass, reduced muscle fiber size, and decreased muscle strength, resulting in persistent physical disability accompanied by sepsis. Systemic inflammatory cytokines are the main cause of SAMW,… read more here.
Keywords: sepsis; muscle wasting; associated muscle; muscle ... See more keywords