Asperspiropene A, a novel fungal metabolite as an inhibitor of cancer-associated mutant isocitrate dehydrogenase 1
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DOI: 10.1039/c6qo00847j
Abstract: In silico screening of an in-house natural product database and confirmatory bioassays led to the identification of asperspiropene A (1) as an inhibitor of cancer-associated mutant IDH1. Compound 1, a meroterpenoid with a highly functionalized… read more here.
Keywords: inhibitor cancer; cancer associated; associated mutant; fungal metabolite ... See more keywords