Diabetes-associated nephropathy and obesity influence COVID-19 outcome in type 2 diabetes patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Community Hospital Internal Medicine Perspectives"
DOI: 10.1080/20009666.2021.1957555
Abstract: ABSTRACT Coronavirus disease 2019 has rapidly spread around the globe and various comorbidities, such as diabetes have been recognized as risk factors for an unfavorable outcome. We analyzed a cohort of COVID-19 patients (n =… read more here.
Keywords: associated nephropathy; outcome; disease; diabetes patients ... See more keywords
APOL1 variants may induce HIV-associated nephropathy during HIV primary infection
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw563
Abstract: HIV-associated nephropathy (HIVAN) is still associated with high mortality, and is usually a late complication of HIV chronic infection. Since 2010, a link has been strongly established between APOL1 genetic variants and HIVAN, especially in… read more here.
Keywords: associated nephropathy; hiv; infection; variants may ... See more keywords
IFNL4 rs368234815 polymorphism does not predict risk of BK virus associated nephropathy after living‐donor kidney transplant: A case‐control study
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DOI: 10.1111/ctr.14663
Abstract: BK polyoma virus (BKPyV) associated nephropathy (BKPyVAN) is a major cause of kidney graft loss in renal transplant patients. Interferons (IFNs) are an important innate immune response against viral infections and genetic polymorphisms of the… read more here.
Keywords: polymorphism; kidney; donor kidney; associated nephropathy ... See more keywords
Levels of donor‐derived cell‐free DNA and chemokines in BK polyomavirus‐associated nephropathy
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DOI: 10.1111/ctr.14785
Abstract: BK polyomavirus‐associated nephropathy (BKPyVAN) carries a risk of irreversible allograft injury. While detection of BK viremia and biopsy assessment are the current diagnostic gold standard, the diagnostic value of biomarkers reflecting tissue injury (donor‐derived cell‐free… read more here.
Keywords: polyomavirus associated; derived cell; cell free; donor derived ... See more keywords
Granulomatous inflammation in BK polyomavirus–associated nephropathy
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DOI: 10.1111/tid.12939
Abstract: Evolving BK polyomavirus–associated nephropathy (BKPyVAN) is characterized by tubulointerstitial inflammation that closely resembles acute T‐cell–mediated allograft rejection if tubulitis is significant. The cellular composition of the inflammation varies during the course of BKPyVAN, and clusters… read more here.
Keywords: associated nephropathy; granulomatous inflammation; inflammation; polyomavirus associated ... See more keywords
Low‐dose cidofovir and conversion to mTOR‐based immunosuppression in polyomavirus‐associated nephropathy
Sign Up to like & getrecommendations! Published in 2019 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13228
Abstract: Polyomavirus‐associated nephropathy (PVAN) remains a relevant complication following kidney transplantation with allograft loss rates of up to 50%. Reduction in overall immunosuppression is a cornerstone of therapy, whereas no specific antiviral regimen has shown conclusive… read more here.
Keywords: associated nephropathy; low dose; dose cidofovir; polyomavirus associated ... See more keywords
BK virus genotypes and humoral response in kidney transplant recipients with BKV associated nephropathy
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DOI: 10.1111/tid.14012
Abstract: Among kidney transplant recipients (KTR) with BK virus associated nephropathy (BKVN), BKV genotypes’ evolution and anti‐BKV humoral response are not well established. We aim to analyze BKV replication and genetic evolution following transplantation, and characterize… read more here.
Keywords: associated nephropathy; kidney transplant; humoral response; transplant recipients ... See more keywords
Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy
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DOI: 10.1155/2022/6934744
Abstract: BK virus-associated nephropathy (BKVN) remains a major infectious complication due to powerful immunosuppression in kidney transplant recipients, and its histologic appearance can mimic rejection, leading to diagnostic and treatment dilemmas thus molecular diagnostic methods would… read more here.
Keywords: biomarker; associated nephropathy; rbbp7; virus associated ... See more keywords
BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy
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DOI: 10.1186/s12879-019-4615-x
Abstract: BackgroundAdjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce. Here, we investigated BKPyV-specific T cell immunity in KT… read more here.
Keywords: associated nephropathy; specific cell; recipients diagnosed; polyomavirus ... See more keywords
HIV-1 Infection of Renal Cells in HIV-Associated Nephropathy.
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DOI: 10.1681/asn.2016111171
Abstract: “If there is one thing the history of evolution has taught us it’s that life will not be contained. Life breaks free, it expands to new territories and crashes through barriers.” (Dr. Ian Malcolm in… read more here.
Keywords: associated nephropathy; hiv infection; cells hiv; infection renal ... See more keywords
AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype.
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DOI: 10.1681/asn.2020050558
Abstract: BACKGROUND Kidney involvement is a feature of COVID-19 and it can be severe in black patients. Previous research linked increased susceptibility to collapsing glomerulopathy, including in patients with HIV-associated nephropathy, to apo L1 (APOL1) variants… read more here.
Keywords: high risk; associated nephropathy; black patients; risk genotype ... See more keywords