Kaposi’s sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009179
Abstract: Primary effusion lymphoma (PEL) is an aggressive B cell lymphoma that is etiologically linked to Kaposi’s sarcoma-associated herpesvirus (KSHV). Despite standard multi-chemotherapy treatment, PEL continues to cause high mortality. Thus, new strategies to control PEL… read more here.
Keywords: associated nuclear; kaposi sarcoma; latency associated; nuclear antigen ... See more keywords
Animal Models of Mitochondrial Diseases Associated with Nuclear Gene Mutations
Sign Up to like & getrecommendations! Published in 2024 at "Acta Naturae"
DOI: 10.32607/actanaturae.25442
Abstract: Mitochondrial diseases (MDs) associated with nuclear gene mutations are part of a large group of inherited diseases caused by the suppression of energy metabolism. These diseases are of particular interest, because nuclear genes encode not… read more here.
Keywords: nuclear gene; associated nuclear; gene mutations; animal models ... See more keywords
TOR1AIP1-Associated Nuclear Envelopathies
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DOI: 10.3390/ijms24086911
Abstract: Human TOR1AIP1 encodes LAP1, a nuclear envelope protein expressed in most human tissues, which has been linked to various biological processes and human diseases. The clinical spectrum of diseases related to mutations in TOR1AIP1 is… read more here.
Keywords: tor1aip1 associated; nuclear envelopathies; associated nuclear;