Distinct T cell subsets in adipose tissue are associated with obesity
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202249990
Abstract: Adipose tissue inflammation is a driving factor for the development of obesity‐associated metabolic disturbances, and a role of adipose tissue T cells in initiating the pro‐inflammatory signaling is emerging. However, data on human adipose tissue… read more here.
Keywords: cell subsets; adipose tissue; associated obesity; tissue ... See more keywords
Adipose tissue LECT2 expression is associated with obesity and insulin resistance in Korean women
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DOI: 10.1002/oby.23445
Abstract: Leukocyte cell‐derived chemotaxin 2 (LECT2) is an obesity‐upregulated hepatokine inducing skeletal muscle insulin resistance. The study's aim was to explore whether LECT2 is expressed in human adipose tissue and whether the expression is dysregulated during… read more here.
Keywords: associated obesity; insulin resistance; adipose tissue; obesity ... See more keywords
Novel 5-HT3 receptor antagonist QCM-4 attenuates depressive-like phenotype associated with obesity in high-fat-diet-fed mice
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4558-0
Abstract: RationaleDepression associated with obesity remains an interesting area to study the biological mechanisms and novel therapeutic intervention.ObjectivesThe present study investigates the effect of a novel 5-HT3 receptor antagonist 3-methoxy-N-p-tolylquinoxalin-2-carboxamide (QCM-4) on several pathogenic markers of… read more here.
Keywords: hfd fed; fed mice; mice; qcm ... See more keywords
Codon usage trend in genes associated with obesity
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Letters"
DOI: 10.1007/s10529-020-02931-z
Abstract: Obesity is not only a social menace but also an economic burden as it reduces productivity and increases health care cost. We used bioinformatic tools to analyze the CUB of obesity associated genes and compared… read more here.
Keywords: codon usage; housekeeping genes; obesity; genes associated ... See more keywords
Role of Obesity in Otorhinolaryngologic Diseases
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DOI: 10.1007/s11882-019-0865-3
Abstract: Purpose of ReviewObesity is a major public health problem associated with various diseases. Improving obesity control and achieving greater patient satisfaction are critical unmet needs. Various otorhinolaryngologic diseases can have negative effects on quality of… read more here.
Keywords: obesity otorhinolaryngologic; role obesity; otorhinolaryngologic diseases; obesity ... See more keywords
An Amino Acid Signature Associated with Obesity Predicts 2-Year Risk of Hypertriglyceridemia in School-Age Children
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05765-4
Abstract: Childhood obesity is associated with a number of metabolic abnormalities leading to increased cardiovascular risk. Metabolites can be useful as early biomarkers and new targets to promote early intervention beginning in school age. Thus, we… read more here.
Keywords: risk; amino acid; acid signature; obesity ... See more keywords
Metabolism and Metabolic Disorders and the Microbiome: The intestinal microbiota associated with obesity, lipid metabolism and metabolic health: pathophysiology and therapeutic strategies.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.10.057
Abstract: Changes in the intestinal microbiome have been associated with obesity and type 2 diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free mice. We review the mechanisms by which alterations… read more here.
Keywords: metabolism metabolic; lipid metabolism; metabolism; metabolic health ... See more keywords
Direction and magnitude of social jetlag are associated with obesity: Results from a sample of hospital employees
Sign Up to like & getrecommendations! Published in 2022 at "Chronobiology International"
DOI: 10.1080/07420528.2022.2090953
Abstract: ABSTRACT Social jetlag, the discrepancy between social and biological timing, has been suggested to disturb metabolic functions. However, the relationship between social jetlag and obesity has been inconsistent in other studies. In this study we… read more here.
Keywords: jetlag associated; associated obesity; social jetlag; jetlag obesity ... See more keywords
Multilevel Factors Associated with Obesity among South Korean Adolescents before and during the COVID-19 Pandemic.
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DOI: 10.1089/chi.2022.0053
Abstract: Background: Coronavirus disease 2019 (COVID-19)-necessitated lockdowns and school closures have limited social interactions among adolescents, which result in unhealthy behaviors. This study compared the multilevel factors associated with obesity among adolescents in South Korea before… read more here.
Keywords: associated obesity; multilevel factors; factors associated; obesity among ... See more keywords
Is Coffee Intake Associated with Obesity-Related Traits? . A Mendelian Randomization/Pleiotropy Approach Using United Kingdom Biobank (UKBB) Database
Sign Up to like & getrecommendations! Published in 2020 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzaa063_068
Abstract: Epidemiological studies suggest that coffee intake (CI) is protective against body weight gain. We explored whether genetic determinants of CI are associated with obesity-related phenotypic traits, primarily body mass Index (BMI). We leveraged information from… read more here.
Keywords: related traits; obesity related; ukbb database; coffee intake ... See more keywords
Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Genetics"
DOI: 10.1186/s12881-020-00999-y
Abstract: Several obesity susceptibility loci in genes, including GNPDA2, SH2B1, TMEM18, MTCH2, CDKAL1, FAIM2, and MC4R, have been identified by genome-wide association studies. The purpose of this study was to investigate whether these loci are associated… read more here.
Keywords: faim2; type diabetes; obesity; associated obesity ... See more keywords