Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain.
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103701
Abstract: BACKGROUND Little is known about chronic cannabis smoking-associated oral microbiome and its effects on central nervous system (CNS) functions. METHODS In the current study, we have analyzed the saliva microbiome in individuals who chronically smoked… read more here.
Keywords: cannabis; associated oral; cannabis smoking; actinomyces meyeri ... See more keywords
Global transcriptional response of oral squamous cell carcinoma cell lines to health-associated oral bacteria - an in vitro study
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DOI: 10.1080/20002297.2022.2073866
Abstract: ABSTRACT Background We have recently demonstrated that health-associated oral bacteria Streptococcus mitis, Neisseria flavescens, and Haemophilus parainfluenzae induce cytotoxicity in oral squamous cell carcinoma (OSCC) cell lines and downregulate CD36, a cancer-assocaited gene. Aim To… read more here.
Keywords: oral bacteria; cell; health associated; cell lines ... See more keywords
Feasibility of oral microbiome profiles associated with oral squamous cell carcinoma
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DOI: 10.1080/20002297.2022.2105574
Abstract: ABSTRACT Objective Recently, the possibility that oral microbiomes is associated with oral squamous cell carcinoma (OSCC) initiation and progression has attracted attention; however, this association is still unclear. Here, we comprehensively analyze the microbiome profiles… read more here.
Keywords: cell carcinoma; oral microbiome; microbiome profiles; squamous cell ... See more keywords
Factors associated with oral health‐related quality of life in patients with diabetes
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DOI: 10.1111/adj.12577
Abstract: BACKGROUND Oral pathologies are prevalent in diabetes, and they may affect the quality of life and patient's perception of their oral health. The aim of this study was to investigate the factors associated with oral… read more here.
Keywords: oral health; associated oral; factors associated; health ... See more keywords
Major bleeding risk associated with oral anticoagulant in real clinical practice. A multicentre 3‐year period population‐based prospective cohort study
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DOI: 10.1111/bcp.14362
Abstract: The objective was to compare major bleeding risk of direct oral anticoagulants (DOACs; per type and dose) with vitamin K antagonists (VKAs), irrespective of indication, using real‐world data. read more here.
Keywords: risk associated; oral anticoagulant; associated oral; major bleeding ... See more keywords
Motivating factors associated with oral pre-exposure prophylaxis use among female sex workers in South Africa
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DOI: 10.1177/13591053211072674
Abstract: To explore the motivating factors that encourage female sex workers to take oral PrEP, despite the challenges that come with adherence. The 39 participants in this study consisted of female sex workers, peer educators, a… read more here.
Keywords: motivating factors; factors associated; sex workers; associated oral ... See more keywords
Variations in protein expression associated with oral cancer
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DOI: 10.3233/thc-236014
Abstract: BACKGROUND: Differential protein expression of the oral microbiome is related to human diseases, including cancer. OBJECTIVE: In order to reveal the potential relationship between oral bacterial protein expression in oral squamous cell carcinoma (OSCC), we… read more here.
Keywords: protein expression; variations protein; expression associated; associated oral ... See more keywords
The Application of Small Molecules to the Control of Typical Species Associated With Oral Infectious Diseases
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DOI: 10.3389/fcimb.2022.816386
Abstract: Oral microbial dysbiosis is the major causative factor for common oral infectious diseases including dental caries and periodontal diseases. Interventions that can lessen the microbial virulence and reconstitute microbial ecology have drawn increasing attention in… read more here.
Keywords: infectious diseases; oral infectious; typical species; species associated ... See more keywords
Serum α-Klotho associated with oral health among a nationally representative sample of US adults
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DOI: 10.3389/fendo.2022.970575
Abstract: Background Low klotho is associated with aging-related traits. However, no study has assessed the association between klotho and oral health in a large sample of population. This study aimed to explore the association between serum… read more here.
Keywords: health; serum klotho; oral health; klotho associated ... See more keywords
Systematic review and meta-analysis of oral squamous cell carcinoma associated oral microbiome
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DOI: 10.3389/fmicb.2022.968304
Abstract: The intersection between the human oral microbiome and oral health is an emerging area of study which has gained momentum over the last decade. This momentum has motivated a search for associations between the oral… read more here.
Keywords: cell carcinoma; oral microbiome; squamous cell; oral squamous ... See more keywords
Pharmacokinetic Exposures Associated With Oral Administration of Sorafenib in Dogs With Spontaneous Tumors
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DOI: 10.3389/fvets.2022.888483
Abstract: Sorafenib is a multi-kinase small molecule inhibitor that targets serine/threonine and tyrosine kinases including the RAF kinase family, VEGFR-2, and PDGFR. The aim of this study was to evaluate the systemic pharmacokinetics of a previously… read more here.
Keywords: administration; serum; pharmacokinetic exposures; sorafenib ... See more keywords