Cilia-Associated Oxysterols Activate Smoothened.
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DOI: 10.1016/j.molcel.2018.08.034
Abstract: Primary cilia are required for Smoothened to transduce vertebrate Hedgehog signals, but how Smoothened accumulates in cilia and is activated is incompletely understood. Here, we identify cilia-associated oxysterols that promote Smoothened accumulation in cilia and… read more here.
Keywords: cilia associated; oxysterols activate; associated oxysterols; hedgehog pathway ... See more keywords