Measuring lipoprotein‐associated phospholipase A2 activity in China: Protocol comparison and recalibration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22628
Abstract: Lp‐PLA2 is a novel inflammation marker in cardiovascular disease. While several manufactures have registered Lp‐PLA2 activity reagents, few studies have investigated the consistency among these assays. In this study, we compared and recalibrated Lp‐PLA2 activity… read more here.
Keywords: associated phospholipase; measuring lipoprotein; phospholipase activity; activity china ... See more keywords
Lipoprotein-associated phospholipase A2 predicts cardiovascular events in dialyzed patients
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DOI: 10.1007/s40620-018-0521-3
Abstract: BackgroundLipoprotein-associated phospholipase A2 (Lp-PLA2) is a serine lipase that enhances the instability of the atherosclerotic plaques. While in the general and cardiac population Lp-PLA2 is recognized as an important determinant of cardiovascular (CV) accidents, no… read more here.
Keywords: nmol min; associated phospholipase; dialyzed patients; acute events ... See more keywords
Impact of tyrosine nitration at positions Tyr307 and Tyr335 on structural dynamics of Lipoprotein-associated phospholipase A2-A therapeutically important cardiovascular biomarker for atherosclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.10.068
Abstract: Protein tyrosine nitration (PTN) is a post translational event which results in the generation of 3-Nitrotyrosine (3-NT). High levels of 3-NT were reported in several human diseases such as Parkinson's disease, Alzheimer's disease, amylotrophic lateral… read more here.
Keywords: lipoprotein associated; tyr307 tyr335; tyrosine nitration; associated phospholipase ... See more keywords
Lipoprotein-associated phospholipase A2: A paradigm for allosteric regulation by membranes
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2102953118
Abstract: Significance Lp-PLA2 is a physiologically important human enzyme and an inflammatory biomarker for assessing risk factors associated with cardiovascular diseases. It is associated with low- and high-density lipoproteins in human plasma and acts on the… read more here.
Keywords: pla2; allosteric regulation; enzyme; specificity ... See more keywords
Lipoprotein-Associated Phospholipase A2 Correlates with Reduced Left Ventricle Ejection Fraction in Hemodialysis Patients.
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DOI: 10.1093/labmed/lmac162
Abstract: OBJECTIVE Reduced left ventricular ejection fraction (LVEF) is common in hemodialysis (HD) patients. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is considered an important determinant of cardiovascular events. The aim of the study was to evaluate the relationship… read more here.
Keywords: lvef; ejection fraction; reduced left; lipoprotein associated ... See more keywords
Evaluation of lipoprotein‐associated phospholipase A2 as a marker for renal microvasculopathy in adolescents with Type 1 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetic Medicine"
DOI: 10.1111/dme.14086
Abstract: To assess the relevance of lipoprotein‐associated phospholipase A2 activity as a diagnostic and prognostic marker for renal microvascular diseases. read more here.
Keywords: lipoprotein associated; marker renal; associated phospholipase; evaluation lipoprotein ... See more keywords